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EBSCO_ocn836864219 |
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20231017213018.0 |
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m o d |
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cr cnu---unuuu |
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130408s2011 nyua ob 001 0 eng d |
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|a 9781617613722
|q (electronic bk.)
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|a 161761372X
|q (electronic bk.)
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|z 9781617612121
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|z 161761212X
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|a DEBBG
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|a (OCoLC)836864219
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|a QP188.P26
|b B48 2011eb
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|a MED
|x 060000
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|a 612.3/4
|2 22
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|a UAMI
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|a Beta cells :
|b functions, pathology, and research /
|c Sarah E. Gallagher, editor.
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|a New York :
|b Nova Biomedical Books,
|c ©2011.
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|a 1 online resource (xi, 176 pages) :
|b illustrations (some color)
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
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|2 rdacarrier
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|a Cell biology research progress
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|a Includes bibliographical references and index.
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|a Print version record.
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|a BETA CELLS: FUNCTIONS, PATHOLOGY AND RESEARCH ; BETA CELLS: FUNCTIONS, PATHOLOGY AND RESEARCH ; Contents ; Preface ; Stress and Pancreatic Ý Cell Function: Role of Glucocortoids, Exercise and Glucolipotoxicity; Abstract ; Introduction Ý Cell Adaptation Ý Cell Mass in Obesity ; Life Cycle of the Ý Cell ; Glucocorticoids and Ý Cell Function ; Direct Effects of Glucocorticoids on Ý Cells ; Indirect Effects of Glucocorticoids on Ý Cell Function ; Role of GRs on Ý Cell Survival and Replication ; Intermittent Stress and Ý Cell Function ; Exercise Intervention on Ý Cell Function.
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|a Exercise Causes Pancreatic Regeneration in Partial Pancreatectomy Models Disposition Index on Ý Cell Function ; Age and Exercise on Ý Cell Function; Glucolipotoxicity on Ý Cell Function ; Glucotoxicity; Lipotoxicity ; Short Term Effects of FFAs ; Long Term Effects of FFAs ; FFAs and ER Stress ; Conclusion ; References ; The Synergistic Effect of Ý Cell Replacement and Immunotherapy on the Treatment of Type 1 Diabetes ; Abstract ; Introduction Ý-Cell Replacement ; Patient-Specific ß-Cells ; 1. Autologous adult stem cell-derived ß-cells ; 2. Induced pluripotent stem cells.
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|a 3. Transdifferentiation-induced Ý-like cells Embryonic Stem Cell-Derived ß-Cells ; Islet Transplantation; Pancreas Transplantation ; Immunotherapy ; Immunopathology of T1D ; Treg-Based Immunotherapy ; 1. Evidence of Treg function in the control of T1D ; 2. Mechanisms of Treg function in T1D ; 3. Therapeutic potential of Tregs on T1D ; Antigen/ Antibody-Based Immunotherapy ; The Potential Synergistic Role of Ý-Cell Replacement and Immunotherapy ; 1. Bi-Directional Actions of Cell-Based Therapy ; 2. Multiple Functions of Immunotherapy ; 3. Temporal and Spatial Actions of Immunotherapy.
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|a VII. Expression of Results and Statistical Analyses 1. Expression of the results ; 2. Statistical analyses ; Results ; I. Effect of Rimonabant Administration (10 Mg/Kg/D) on Body Weight of ZDF Rats; II. Rimonabant Administration (10 Mg/Kg/D) Prevents the Elevation of Blood Glucose Levels of ZDF Rats ; III. Rimonabant Administration (10 Mg/Kg/D) Reduces the Decline of Insulinemia of ZDF Rats ; IV. Rimonabant Administration (10 Mg/Kg/D) Reduces Cell Dysfunction in ZDF Rats; 1. Insulin secretion during static incubation of islets isolated from ZDF rats treated for 2 weeks.
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|a And Conclusion Acknowledgments ; References; Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes and Ý Cell Dysfunction in Zucker Diabetic Fatty Rats ; Abstract ; Methods ; Results ; Introduction ; Materials and Methods ; I. Drugs and Reagents ; II. Animals ; III. Treatment and Follow-up ; IV. Islet Isolation ; V. Glucose-Stimulated Insulin Secretion (GSIS) Assessment by Static Incubation of Isolated ZDF Rat Islets; VI. Glucose-Stimulated Insulin Secretion (GSIS) Assessment by Perifusion of Isolated ZDF Rat Islets.
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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|a Pancreatic beta cells.
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|a Diabetes.
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|a Islets of Langerhans
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|a Cellules bêta des îlots de Langerhans.
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|a MEDICAL
|x Nutrition.
|2 bisacsh
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|a Diabetes
|2 fast
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|a Pancreatic beta cells
|2 fast
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700 |
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|a Gallagher, Sarah E.
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776 |
0 |
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|i Print version:
|t Beta cells.
|d New York : Nova Biomedical Books, ©2011
|z 9781617612121
|w (DLC) 2010027623
|w (OCoLC)649077700
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830 |
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|a Cell biology research progress.
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856 |
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|u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=540538
|z Texto completo
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938 |
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