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Beta cells : functions, pathology, and research /

And Conclusion Acknowledgments ; References; Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes and Ý Cell Dysfunction in Zucker Diabetic Fatty Rats ; Abstract ; Methods ; Results ; Introduction ; Materials and Methods ; I. Drugs and Reagents ; II. Animals ; III. Treatmen...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Gallagher, Sarah E.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Biomedical Books, ©2011.
Colección:Cell biology research progress.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Beta cells :  |b functions, pathology, and research /  |c Sarah E. Gallagher, editor. 
260 |a New York :  |b Nova Biomedical Books,  |c ©2011. 
300 |a 1 online resource (xi, 176 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Cell biology research progress 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a BETA CELLS: FUNCTIONS, PATHOLOGY AND RESEARCH ; BETA CELLS: FUNCTIONS, PATHOLOGY AND RESEARCH ; Contents ; Preface ; Stress and Pancreatic Ý Cell Function: Role of Glucocortoids, Exercise and Glucolipotoxicity; Abstract ; Introduction Ý Cell Adaptation Ý Cell Mass in Obesity ; Life Cycle of the Ý Cell ; Glucocorticoids and Ý Cell Function ; Direct Effects of Glucocorticoids on Ý Cells ; Indirect Effects of Glucocorticoids on Ý Cell Function ; Role of GRs on Ý Cell Survival and Replication ; Intermittent Stress and Ý Cell Function ; Exercise Intervention on Ý Cell Function. 
505 8 |a Exercise Causes Pancreatic Regeneration in Partial Pancreatectomy Models Disposition Index on Ý Cell Function ; Age and Exercise on Ý Cell Function; Glucolipotoxicity on Ý Cell Function ; Glucotoxicity; Lipotoxicity ; Short Term Effects of FFAs ; Long Term Effects of FFAs ; FFAs and ER Stress ; Conclusion ; References ; The Synergistic Effect of Ý Cell Replacement and Immunotherapy on the Treatment of Type 1 Diabetes ; Abstract ; Introduction Ý-Cell Replacement ; Patient-Specific ß-Cells ; 1. Autologous adult stem cell-derived ß-cells ; 2. Induced pluripotent stem cells. 
505 8 |a 3. Transdifferentiation-induced Ý-like cells Embryonic Stem Cell-Derived ß-Cells ; Islet Transplantation; Pancreas Transplantation ; Immunotherapy ; Immunopathology of T1D ; Treg-Based Immunotherapy ; 1. Evidence of Treg function in the control of T1D ; 2. Mechanisms of Treg function in T1D ; 3. Therapeutic potential of Tregs on T1D ; Antigen/ Antibody-Based Immunotherapy ; The Potential Synergistic Role of Ý-Cell Replacement and Immunotherapy ; 1. Bi-Directional Actions of Cell-Based Therapy ; 2. Multiple Functions of Immunotherapy ; 3. Temporal and Spatial Actions of Immunotherapy. 
505 8 |a VII. Expression of Results and Statistical Analyses 1. Expression of the results ; 2. Statistical analyses ; Results ; I. Effect of Rimonabant Administration (10 Mg/Kg/D) on Body Weight of ZDF Rats; II. Rimonabant Administration (10 Mg/Kg/D) Prevents the Elevation of Blood Glucose Levels of ZDF Rats ; III. Rimonabant Administration (10 Mg/Kg/D) Reduces the Decline of Insulinemia of ZDF Rats ; IV. Rimonabant Administration (10 Mg/Kg/D) Reduces Cell Dysfunction in ZDF Rats; 1. Insulin secretion during static incubation of islets isolated from ZDF rats treated for 2 weeks. 
520 |a And Conclusion Acknowledgments ; References; Antagonizing the Endocannabinoid Pathway Prevents the Development of Diabetes and Ý Cell Dysfunction in Zucker Diabetic Fatty Rats ; Abstract ; Methods ; Results ; Introduction ; Materials and Methods ; I. Drugs and Reagents ; II. Animals ; III. Treatment and Follow-up ; IV. Islet Isolation ; V. Glucose-Stimulated Insulin Secretion (GSIS) Assessment by Static Incubation of Isolated ZDF Rat Islets; VI. Glucose-Stimulated Insulin Secretion (GSIS) Assessment by Perifusion of Isolated ZDF Rat Islets. 
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650 0 |a Pancreatic beta cells. 
650 0 |a Diabetes. 
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