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Microglia : biology, functions and roles in disease /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hauppauge, N.Y. :
Nova Science Publisher's,
©2012.
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| Colección: | Cell biology research progress.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- MICROGLIA: BIOLOGY, FUNCTIONS AND ROLES IN DISEASE; MICROGLIA: BIOLOGY, FUNCTIONS AND ROLES IN DISEASE; LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA; CONTENTS; PREFACE; REFERENCE; Chapter 1: MICROGLIA IN THE DEVELOPING BRAIN; ABSTRACT; ABBREVATIONS; I. INTRODUCTION; II. MICROGLIAL PHENOTYPES; 1. Amoeboid Microglia; 2. Ramified Microglia; III. LOCALISATION OF MICROGLIAL CELLS IN THE DEVELOPING BRAIN; 1. Developing Cerebrum; 2. Developing Cerebellum; IV. ULTRASTRUCTURAL FEATURES OF AMCS; V. FUNCTIONS OF MICROGLIA IN THE DEVELOPING BRAIN; 1. Phagocytosis; 2. Immune Functions of Microglia.
- 3. Iron Acquisition4. Nitric Oxide Production; 5. Growth Factors; 6. Microglia in Myelination; 7. Microglia in Neurogenesis and Astrogenesis; 8. Microglia and Synapses; 9. Microglia and Vascularisation; XIII. MICROGLIA IN DISORDERS OF THE DEVELOPING BRAIN; 1. Infections; 2. Periventricular White Matter Damage; 3. Epilepsy; 4. Autism; CONCLUSION; REFERENCES; Chapter 2: THE MYSTIC EMBRYONIC MICROGLIA: ITS ORIGIN, FUNCTION AND SEEDING; ABSTRACT; INTRODUCTION; NEUROECTODERMAL ORIGIN OF MICROGLIA; MONOCYTIC ORIGIN OF MICROGLIA; MESODERMAL ORIGIN OF MICROGLIA; TROUBLESHOOTING.
- MIGRATION CHARACTERISTICS OF MICROGLIAIf Microglia Use the Blood Vessels; If Microglia Are Derived from Meningeal Sources; DEVELOPMENTAL ROLES OF MICROGLIA; Angiogenesis; Scavengers of Cell Debris; Synaptics Pruning; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 3: SOLDIERS OF THE NERVOUS SYSTEM: MICROGLIA IN SURVEILLANCE, OFFENSE AND DEFENSE; ABSTRACT; SOLDIERS OF THE NERVOUS SYSTEM: MICROGLIA IN SURVEILLANCE, OFFENSE AND DEFENSE; MARKERS OF MICROGLIA; MICROGLIA AS SURVEILLANCE CELLS; MICROGLIA AND DEVELOPMENT; MICROGLIA AND DISEASE; Neuron-Glia Interactions; Microglia and Pathogens.
- Microglia and NeuropathogenesisMICROGLIA AND REGENERATION; THERAPEUTIC APPROACHES AND CHALLENGES; CONCLUSIONS; REFERENCES; Chapter 4: MICROGLIA SECRETOME: FROM NEUROTOXINS TO NEUROTROPHINS; ABSTRACT; 1. INTRODUCTION; 2. MICROGLIA SECRETOME; 3. IDENTIFICATION OF SECRETOME COMPONENTS; 4. NEUROTROPHIC FACTORS; 4.1. Neuroprotective Cytokines; 4.2. Growth Factors; 4.3. Neuroprotective Enzymes; 4.4. Other Potential Neuroprotective Substances; 5. NEUROTOXIC FACTORS; 5.1. Reactive Molecules; 5.2. Neurotoxic Enzymes; 5.3. Other Potential Neurotoxic Substances; 6. FACTORS WITH MULTIPLE EFFECTS.
- 6.1. Cytokines6.2. Cathepsins and Cystatins; 6.3. Other Substances with Multiple Effects; CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 5: THE ROLE OF MICROGLIA IN NEURODEGENERATIVE DISEASE; ABSTRACT; 1. INTRODUCTION; 2. NORMAL IMMUNE FUNCTIONS OF MICROGLIA; 2.1. Microglia as Mediators of CNS Inflammation; 2.2. The In Vivo Visualization of Activated Microglia; 3. MICROGLIA IN NEURODEGENERATIVE DISEASE; 3.1. Alzheimer's Disease and other Dementias; 3.2. Parkinson's Disease and Related Disorders; 3.3. Huntington's Disease; 3.4. Multiple Sclerosis; 3.5. Amyotrophic Lateral Sclerosis.