Advances in medicine and biology. Volume 47 /
This continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include the comprehensive role of oxygenation in the...
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
New York :
Nova Science Publishers,
©2012.
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Colección: | Advances in Medicine and Biology.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ADVANCES IN MEDICINE AND BIOLOGY VOLUME 47
- ADVANCES IN MEDICINE AND BIOLOGY VOLUME 47
- Contents
- Preface
- Comprehensive Role of Oxygenation in the Regulation of Erythropoiesis
- Abstract
- Introduction
- The Main Systemic Regulator of Erythropoiesis-Erythropoietin
- The Role of Cellular Detectors of Oxygen in Regulation of Erythropoiesis
- Oxygen Sensing and Iron Homeostasis
- Level of Oxygenation and Synthesis of Heme and Hemoglobin
- Cytokine Stimulator of Erythropoiesis, with Respect to O2 Concentration
- ""Oxygenation Level and Functional Characteristics of Hematopoietic Niche Stromal Cells""""Oxygenation as a Physiological Regulator of Functional Erythroid Cells� Characteristics in the Course of Ontogenesis ""; ""Influence of Oxygenation Level on Proliferation and Differentiation of Erythroid Progenitors and Maturation of Erythroid Precursors""; ""Transcriptional Regulation: Influence of Oxygenation Level on GATA-1 Expression ""; ""Other Pathways Involved in the O2 Mediated Regulation of Erythropoiesis ""; ""Notch Signalization""; ""Erythropoiesis and Oxidative Stress""; ""Conclusion ""
- Acknowledgments References
- Radiation-Related Toxicity in 3D Conformal Radiotherapy, Intensity-Modulated Radiotherapy, and Proton Beam Therapy for Lung Cancer
- Introduction
- Radiation Pneumonitis
- Incidence and Clinical Description
- Grading of RP
- Imaging of RP
- Impact of RP on Lung Function
- Treatment of RP
- Factors Associated with RP
- Clinical Factors
- Dosimetric Factors
- DVH Parameters
- Quantitative Analysis of Normal Tissue Effects in the Clinic Recommendations
- Single-Nucleotide Polymorphisms and Risk of RP
- Reducing RP Risk Using Advanced Radiation TechnologySummary
- Radiation Esophagitis
- Incidence and Clinical Description
- Clinical and Dosimetric Predictors of Radiation Esophagitis: QUANTEC Recommendations
- The Role of Fractionation Schedules in Radiation Esophagitis
- The Role of Chemotherapy in Radiation Esophagitis
- The Role of Radioprotective Agents in Radiation Esophagitis
- Molecular Predictors of Radiation Esophagitis
- Cardiotoxicity
- Incidence and Clinical Manifestations
- Molecular Mechanisms of Cardiac Injury Induced by RT
- ""Clinical and Dosimetric Predictors of Cardiotoxicity: QUANTEC Recommendations """"Imaging of Cardiac Sequelae of RT ""; ""Blood Biomarkers in Predicting Cardiotoxicity""; ""Advanced Technology in Radiation Reduced Toxicity: Comparison of 3D-CRT, IMRT, and PBT ""; ""Comparison of 3D-CRT and IMRT ""; ""Comparison of IMRT and PBT ""; ""Summary Recommendations: Dose Constraints""; ""Management of Thoracic RT�s Toxic Effects ""; ""References ""; ""Erythropoiesis: Development, Regulation, and Disorders ""; ""Abstract ""; ""Introduction""; ""Historical Review""; ""Assays for Erythropoietin ""