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Advances in medicine and biology. Volume 53 /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Berhardt, Leon V.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science Publishers, ©2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ADVANCES IN MEDICINE AND BIOLOGY ; ADVANCES IN MEDICINE AND BIOLOGY ; Contents ; Preface ; Mesenchymal Stem Cells and Type 1 Diabetes Mellitus ; Abstract ; Introduction ; MSCs: Definition and Identification ; Regenerative Capacities and Homing Characteristics ; Immunosuppressive Potentials ; Differentiation Potentials of MSCs into Surrogate Ý-Cells ; Genetic Manipulation ; MSCs Plus Islet Cell Transplantation ; Pancreatic MSCs; Diabetic MSCs ; Umbilical Cord Blood MSCs (UCB-MSCs) ; Wharton's Jelly MSCs (WJ-MSCs) ; MSCs and Complications of Diabetes ; Diabetic Cardiomyopathy (DCM)
  • Diabetic Nephropathy Diabetic Retinopathy; Safety Issues ; Clinical Trials ; Controversies ; Conclusion ; References; Falls in Elderly Patients ; Abstract ; Introduction; Definition and Dimension of the Problem ; Etiology and Factors Predisposing to Falls ; Consequences of the Falls ; Diagnosis of Risk for Falls (Fall Risk-Prediction Tools) ; Assessing for Risks of Anticipated Physiological Falling ; 2. Strategies to Prevent Unanticipated Physiological and Accidental Falls ; Fall Prevention Strategies; Intervention Plans; Conclusion ; Acknowledgment ; References.
  • Recent Advances in Scleroderma Pulmonary FibrosisAbstract ; 1. Introduction; 2. SSc-Associated Interstitial Lung Disease vs. SSc-Associated Pulmonary Arterial Hypertension ; 3. Lung Injury: Repair, Remodeling, and Regeneration ; a) The Inflammatory Phase ; b) The Proliferative Phase ; c) The Remodeling Phase ; 4. Mouse Models and What They Tell Us about SSc-Mediated Interstitial Lung Disease ; 5. Animal Models of SSc Vasculopathy ; a) Fos-Related Antigen-2 (FRA-2) Transgenic Mouse Model ; b) Friend Leukemia Integration Factor-1 (Fli-1) Conditional Knockout Mimics SSc Vasculopathy.
  • C) Endothelin-1 (ET-1) Gene and the Tsk/+ Mouse 6. Animal Models of SSc Pulmonary Fibrosis ; a) Peroxisome Proliferator-Activated Receptor-Gamma (PPARÞ) ; b) Alpha-Melanocyte Stimulating Hormone (A-MSH) ; c) Early Growth Response Gene (Egr-1) ; d) The Interactions between Macrophage Chemoattractant Protein-1, Basic Fibroblast Growth Factor, and Connective Tissue Growth Factor to Establish Persistent Fibrosis; 7. The Inflammasomes ; a) Caspase-1; b) IL-1Ý and IL-18 ; c) IL-1Ý And IL-18 are Known to Induce Fibrosis ; d) NLRP3 Inflammasome and Pulmonary Fibrosis.
  • 8. NLRP3 Inflammasome-Mediated Fibrosis in Other Tissues 9. Novel Inhibitors of Fibrosis ; Conclusion ; References ; Major Histocompatibility Complex: Biology, Functions and Roles in Disease ; Abstract ; Introduction; Evolution of MHC Molecules ; Comparative Genomic Analysis of MHC Region across Primates ; Comparative Genomic Analysis of Mammalian and Non-Mammalian Vertebrate MHC Region ; How the MHC Genes Emerged in Vertebrates ; Evolutionary Forces Maintaining Polymorphism at the MHC Loci ; Biology of MHC Class I Molecules ; Biology of MHC Class II Molecules.