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Horizons in neuroscience research. Volume 8 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hauppauge, N.Y. : Lancaster :
Nova Science ; Gazelle [distributor],
2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ""HORIZONS IN NEUROSCIENCE RESEARCH VOLUME 8 ""; ""HORIZONS IN NEUROSCIENCE RESEARCH VOLUME 8 ""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Regulation of Neuronal Morphology and Plasticity by Small GTP-Binding Proteins: Implications for Autism and Mental Retardation Disorders""; ""1Department of Pharmacological and Pharmaceutical Sciences, University of Houston.""; ""521 Science and Research Bldg 2, Houston, TX, US""; ""2Department of Biology and Biochemistry, University of Houston""; ""369 Science and Research Bldg 2, Houston, TX, US""
- ""3Department of Psychology, University of Houston""""126 Heyne Building, Houston, TX, US""; ""Abstract""; ""Introduction""; ""Autism Spectrum Disorders""; ""Small GTPases""; ""Rac, Cognition and Autism""; ""Regulation of Neuronal Morphology and Plasticity by Rac1""; ""Regulation of Learning and Memory by Rac1""; ""Fragile X Syndrome""; ""The Fmr1 Knockout Mice as an Animal Model for Fragile X Syndrome""; ""A Possible Link between Rac1 and Fragile X Syndrome""; ""Methodology""; ""Animals""; ""Generation of Rac1 Deficient Mice (Rac1 Mutant or Rac1 Knockout)""; ""Fmr1 Knockout Mouse""
- ""Isolation of Brain and Other Organs and Preparation of Hippocampal Slices""""Gross Morphology of the Hippocampus""; ""In Situ Hybridization""; ""Affinity Purification Assay""; ""Immunoblot Analysis""; ""Immunocytochemistry""; ""Neuronal Staining and Imaging""; ""Dendritic Spine Analysis""; ""Electrophysiological Recordings""; ""Behavioral Tests""; ""Open Field Testing""; ""Accelerating Rotating Rod Test""; ""Pre-Pulse Inhibition of Startle Response""; ""Hot Plate Test""; ""The Light-Dark Test""; ""The Elevated Plus Maze""; ""Fear Conditioning""; ""Morris Water Maze""; ""Data Analysis""
- ""Results""""Modulation of Rac1 Function by NMDA Receptors""; ""Critical Role of Rac1 in Neuronal Morphology""; ""Critical Role of Rac1 in Plasticity""; ""Critical Role of Rac1 in Learning""; ""Modulation of Neuronal Morphology and Plasticity by Rac1: A Role in Neurodevelopmental Disorders, Autism and Cognitive Disability""; ""Rac1 in Development""; ""Rac1 in Fragile X Syndrome Pathology""; ""Targeting Hyperactivation of Rac1 as a Novel Therapeutic Strategy for FXS""; ""Conclusion""; ""Acknowledgements""; ""References""
- ""Memory and Cognitive Dysfunctions in Alzheimer�s Disease Are Inextricably Intertwined with Neuroinflammation due to Aging, Obesity, Obstructive Sleep Apnea, and other Upstream Risk Factors""""Abstract""; ""1. Introduction""; ""2. Ageing and Inflammatory Stimulation""; ""3. Cigarette Smoking and Inflammatory Stimulation""; ""4. Obesity and Inflammatory Stimulation""; ""4A. Gut Inflammation in Obesity and Pro-inflammatory Cytokines""; ""4B. NSAIDs-induced Gut Inflammation""; ""5. Obstructive Sleep Apnea and Inflammatory Stimulation""; ""6. Snoring and Inflammation""