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Head and neck cancer recurrence : evidence-based, multidisciplinary management /

"Over the past 5 to 10 years, organ preservation techniques using chemoradiotherapy have gained considerable popularity as first-line treatment of head and neck cancer, especially for oropharyngeal, laryngeal, and hypopharyngeal cancer. This trend is now increasing with more intensified chemora...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Mehanna, Hisham M. (Editor ), Ang, K. K. (K. Kian) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Stuttgart : Thieme, 2012.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Head and Neck Cancer Recurrence: Evidence-based, Multidisciplinary Management; Title Page; Copyright; Contributors; Preface; Acknowledgments; Contents; 1 Introduction; Clinical Assessment and Imaging Evaluation of Recurrence; Principles of the Assessment of Potential Recurrence; History and Examination; Previous Treatment Records; Imaging; Examination under Anesthetic; Needle or Open Biopsy; 2 Molecular Biology of Recurrence; Introduction; The Biology of Treatment Resistance; Activation of Alternative Signaling Pathways; Biological Processes Involved in Metastasis; Conclusions.
  • 3 Imaging Modalities for Head and Neck Cancer RecurrenceTherapy-related Changes in the Head and Neck Region; Imaging Modalities for Detection of Recurrence; Imaging for Recurrence at Specific Sites; 4 Concurrent Chemotherapy and Re-irradiation for Recurrent Head and Neck Cancer; Introduction; Reasons for Tumor Recurrence Following Definitive Therapy; Regimens for Concurrent Chemotherapy with Re-irradiation; Evidence for Concurrent Chemotherapy with Re-irradiation; Brachytherapy for Recurrent Head and Neck Cancer; Patient Selection and Prognostic Factors.
  • Simulation and Planning for Re-irradiationTreatment Volume Definition; Beam Arrangement; Advances in Delivery of Radiation; New Approaches to CRRT; Conclusion; 5 Systemic Therapy in the Treatment of Recurrent and Metastatic Head and Neck Carcinoma; Patient's Clinical Profile and Assessment; Clinical Decision Making; Medical Treatment; Special Issues in End-of-Life Supportive Care; 6 Principles and Concepts of Reconstruction in the Recurrent Setting; Introduction; Issues in Surgical Approach-Impact of Previous Treatment; Management of the Vessel-depleted Neck.
  • Site-specific Defect ConsiderationsConclusion; 7 Patient Selection for Treatment; Introduction; Assessment of the Recurrent Cancer; Factors Involved in Treatment Selection; Involving the Patient in the Decision-making Process; Treatment Options; 8 Recurrent Laryngeal Cancer; Introduction; Epidemiology; Diagnosis of Recurrent Laryngeal Cancer; Staging of Recurrent Laryngeal Cancer; Principles of Management; Surgical Management of Recurrent Disease; 9 Management of Recurrent Hypopharyngeal Cancer; Incidence and Patterns of Recurrence in Hypopharyngeal Cancer; Detection of Recurrent Disease.
  • Principles of ManagementSurgical Techniques of Salvage Pharyngolaryngectomy; Re-irradiation for Recurrent Hypopharyngeal Cancer; 10 Carcinoma of the Oral Cavity; Introduction; Posttreatment Surveillance; Diagnosis of Recurrence; Principles of Management; Surgical Approaches and Techniques; Outcomes; 11 Carcinoma of the Oropharynx; Epidemiology; Prognostic Factors; Investigations; Principles of Management; Outcomes; 12 Management of Nodal Recurrence; Introduction; Incidence and Distribution of Nodal Recurrence; Evaluation of Nodal Recurrence; Management; Special Considerations; Outcomes.