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Advances in genetics research. Vol. 7 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Nova Science Publishers, Inc.,
Ã2012.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ADVANCES INGENETICS RESEARCHVOLUME 7; ADVANCES IN GENETICS RESEARCH; Library of Congress Cataloging-in-Publication Data; Contents; Preface; List of Contributors; Gene Therapy for HepatocyteGrowth Factor Supplementationin the Rescue of IncurableOrgan Diseases; Abstract; 1. Introduction; 2. HGF and its Biological Property; 2.1. Effect of HGF on Parenchymal Cells; 2.2. Anti-Fibrotic Activity of HGF; 2.3. Anti-Inflammatory Action of HGF toward Macrophages; 2.4. Angiogenic Action of HGF toward Vascular Cells; 3. HGF-Deficiency as a PahtogeneticSignificance; 3.1. Kidney; 3.2. Liver and Lungs.
- 3.3. Other Organs4. Supplement therapy with RecombinantHGF Protein; 4.1. Acute Diseases; 4.2. Fibrotic Diseases; 4.3. Cardiovascular and Neural Diseases; 5. HGF Gene Therapy for Fibrotic and Obstructive Diseases; 5.1. Fibrotic Diseases; 5.2. Chronic Obstructive Pulmonary Disease (COPD); 5.3. Peripheral Artery Disease (PAD); 6. HGF Gene Drug for Treating Cardiacand Neural Diseases; 6.1. Heart Diseases; 6.1.1. Chronic Myocardial Infarction (MI); 6.1.2. Dilatative Cardiomyopathy; 6.2. Neural Diseases; 6.2.1. Chronic Cerebral Infarction (CI); 6.2.2. Neuro-Degenerative Diseases.
- 6.2.3. Spinal Cord Injury (SCI)6.2.4. Other Neural Diseases; 7. Other Applications for HGFGene Therapy; 7.1. Diabetes Mellitus (DM) and its Complications; 7.2. Inflammatory Bowel Diseases (IBD); 7.3. Organ Transplantation; 7.4. Others; 8. Vector and New Device for SupportingHGF Gene Therapy; 8.1. Non-Viral Vectors; 8.2. Virus Vectors; 8.3. Gene Carrier; 8.4. New Device; 9. Clinical Studies and Future Perspective; References; Targeting Bacteriocin Genes inLactic Acid Bacteria
- What WeNeed To Know; Abstract; Introduction; Bacteriocin Genes Reported in LacticAcid Bacteria.
- Bacteriocin Detected by PCR and Confirmed Expression by otherApproachesConclusions; References; Nanomedicine Based Strategiesfor RNA Therapeutics; Abstract; Introduction; Basic Principle and Mechanism of RNA Interference; Advantages and Limits of Nanoparticles; Barriers to siRNA Delivery; In Vitro Barriers; In Vivo Barriers; Strategies for Targeted siRNA Delivery; Peptides; Transferrin; Antibodies; Targeting Ligands; Delivery of siRNA with PolycationicVectors; Polyethylenimine; Chitosan; Poly-L-Lysine; Cyclodextrin; Protamine; Encapsulation of siRNA withinNanoparticles; Future Perspectives.