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Advances in medicine & biology. Volume 44 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hauppauge, N.Y. : Lancaster :
Nova Science ; Gazelle [distributor],
2012.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ADVANCES IN MEDICINE AND BIOLOGY ; ADVANCES IN MEDICINE AND BIOLOGY ; Contents; Preface; C. Elegans and Neurodegeneration in Caenorhabditis Elegans: Anatomy, Life Cycles and Biological Functions; 1. Introduction; 2. Alzheimer's Disease; Disease-Linked Mutations and Neurodegeneration; Screens Identifying Modifier Genes; Chemical- and Metal-Induced Neurodegeneration; Pharmacological Compounds and Neurodegeneration; 3. Parkinson's Disease; Disease-Linked Mutations and Neurodegeneration; Autosomal Dominant Genes; Autosomal Recessive Genes; Screens Identifying Modifier Genes.
- Chemical- and Metal-Induced NeurodegenerationPharmacological Compounds and Neurodegeneration; 4. Huntington's Disease; Disease-Linked Mutations and Neurodegeneration; Expression of Isolated PolyQ; Expression of Htt N-Terminal Fragments; Screens Identifying Modifier Genes; Pharmacological Compounds and Neurodegeneration; 5. Amyotrophic Lateral Sclerosis (ALS); Disease-Linked Mutations and Neurodegeneration; Screens Identifying Modifier Genes; 6. Spinal Muscular Atrophy (SMA); Disease-Linked Mutations and Neurodegeneration; Screens Identifying Modifier Genes.
- Pharmacological Compounds and NeurodegenerationConclusions; Acknowledgments; References; Caenorhabditis elegans as a Host Model for Studying the Pathogenicity and Virulence of Staphylococcus aureus; Abstract; Introduction; Staphylococcus aureus and MRSA; S. aureus Virulence and Pathogenicity; Animal Models for S. aureus; Biology of C. elegans; Worm Anatomy and Life Cycle; C. elegans Defense Mechanism; C. elegans as a Host Model for Studying Bacterial Pathogenesis; C. elegans as a Host Model for Studying S. aureus Pathogenesis.
- The C. elegans Host Model Correlates with Clinical Manifestations of S. aureus Infections in a Large Canadian Health Care RegionMRSA Strains with Distinct Nematocidal Activities Have Different; Genetic Backgrounds; Validation of the C. elegans Model Using Canadian Major Epidemic; MRSA Strains; Validation of the C. elegans Host Model in a Neonatal Intensive Care Unit (NICU) Outbreak in Toronto; MSSA Strains with Distinct Nematocidal Activities Have Different Genetic Backgrounds; Accumulation of S. aureus inside the Digestive Tract Is Correlated with Nematocidal Activity.
- S. aureus Lysozyme Resistance Contributes S. aureus Lysozyme Resistance ContributesA Lysozyme-Sensitive S. aureus Mutant Exhibited Reduced Accumulation inside the C. elegans Gut; Mutation of Lysozyme Genes in C. elegans Reduced Nematodes Fitness against S. aureus; Conclusion; References; Understanding the Molecular Basis for the Hazards Associated with Nevirapine Treatment; Abstract; Overview; Nevirapine Pharmacokinetics and Metabolism; Nevirapine Toxicity; Nevirapine Bioactivation; Synthetic Biomarkers as Tools for Biomonitoring Nevirapine Toxicity; Acknowledgments; References.