Regulatory T cells /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hayashi, Ren S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science Publishers, c2011.
Colección:Cell biology research progress.
Immunology and immune system disorders.
Temas:
T cells.
Immune response > Regulation.
Réaction immunitaire > Régulation.
MEDICAL > Immunology.
Immune response > Regulation
T cells
Acceso en línea:Texto completo
Tabla de Contenidos:
  • REGULATORY T CELLS
  • REGULATORY T CELLS
  • Contents
  • Preface
  • T Helper 17 Cells Interplay with CD4+CD25highFoxp3+ Regulatory T cells in Regulating Autoimmune Inflammation
  • 1. Abstract
  • 2. Introduction
  • 3. Comparison of the New Multi-Subset Paradigm to the old Th1-Th2 Paradigm
  • 3.1. Imperfect Th1-Th2 Paradigm
  • 3.2. New CD4+ Th Subsets â€? Tregs, Th17, Th9, Tfh, IL-10 IFN-Gamma-Secreting CD4+ T cells and CD4+CD28null T Cells
  • 3.2.1. Tregs
  • 3.2.2. Th17
  • 3.2.3. Th9
  • 3.2.4. Tfh
  • 3.2.5. IL-10- IFN-gamma-secreting CD4+ T cells
  • 3.2.6. CD4+CD28null T cells 4. Structural Characters of IL-17 Family Cytokines
  • 5. Th17 Cells, a New Proinflammatory and Autoimmune CD4+ T Cell Subset
  • 6. Wide Spectrum Effects of IL-17 on Various Cell Types and Tissues
  • 6.1. Synovial Stromal Cells
  • 6.2. Fibroblasts
  • 6.3. Endothelial Cells
  • 6.4. Vascular Smooth Muscle Cells (VSMCs)
  • 6.5. Monocytic Cells and Macrophages
  • 6.6. Structural Lung Cells
  • 7. Signaling Pathways Initiated by Binding of IL-17 Cytokines and IL-17 Receptors
  • 7.1. IL-17 Receptor Family
  • 7.2. IL-17 Receptor Complex Components 7.3. IL-17 Receptor Signaling
  • 8. Th17/IL-17-Mediated Inflammations
  • 8.1. Experimental Autoimmune Encephalomyelitis (EAE)/Multiple Sclerosis
  • 8.2. Inflammatory Skin Disease in Mice and Psoriasis in Humans
  • 8.3. Inflammatory Bowel Disease (IBD) [1]
  • 8.4. Experimental Arthritis/Rheumatoid Arthritis [1]
  • 8.5. Atherosclerosis
  • 8.6. Diabetes
  • 9. Protective Roles of IL-17 in Infections
  • 10. Interplay between Th17 Cells and Tregs
  • 10.1. Recent Progress in Characterizing Tregs
  • 10.2. Reciprocally Interconnected Th17 and Tregs10.3. Inhibition of Th17 by Tregs
  • Conclusion
  • References
  • Human CD8 Tregs as Contender in Chronic Persisting Infections
  • Abstract
  • Introduction
  • Treg Subsets, Markers and Plasticity
  • CD8 Tregs in Human Disease
  • Mechanism of Suppression by CD8+ Tregs
  • The CCL4-CCR5 Axis as a New Player in CD8 Treg Mediated Suppression
  • Evidence for Involvement of Tregs in Chronic Human Infectious Diseases
  • Human CD4+ Tregs in Infectious Diseases
  • Mycobacterial infections
  • Parasitic infections
  • Other bacterial infections Viral infections
  • Human CD8+ Tregs in Infectious Diseases
  • Mycobacterial infections
  • Viral infections
  • Antigen Specificity & HLA Restriction of Tregs
  • Location of Tregs Suggests Significant Role in Containment of Pathogens, but Timing of Treg Activity is Crucial
  • Tregs in TB Vaccination May Inhibit TB Protection: Lessons for Rational Vaccine Design
  • Conclusion
  • Acknowledgments
  • References
  • Role of Regulatory t Cells in the Treatment of Multiple Sclerosis
  • Abstract
  • 1. Introduction

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