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Chemogenomics : knowledge-based approaches to drug discovery /
In the post-genomic era, one of the key challenges for drug discovery is making optimal use of the comprehensive genomic data available after the elucidation of the human genome and others in order to identify effective new medicines. Addressing this challenge, "Chemogenomics" aims to iden...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London : Hackensack, NJ :
Imperial College Press ; Distributed by World Scientific Pub.,
©2006.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Ch. 1. Small molecules for chemogenomics-based drug discovery / Edgar Jacoby ... [et al.]
- ch. 2. Mapping the chemogenomic space / Jordi Mestres
- ch. 3. Natural product scaffolds and Protein Structure Similarity Clustering (PSSC) as inspiration sources for compound library design in chemogenomics and drug development / Frank J. Dekker, Stefan Wetzel and Herbert Waldmann
- ch. 4. A reductionist approach to chemogenomics in the design of drug molecules and focused libraries / Roger Crossley and Martin Slater
- ch. 5. In silico screening of the protein structure repertoire and of protein families / Didier Rognan
- ch. 6. New methods for similarity-based virtual screening / Jérôme Hert, Peter Willett and David J. Wilton
- ch. 7. Structural informatics: chemogenomics in silico / Derek A. Debe, Kevin P. Hambly and Joseph F. Danzer
- ch. 8. Construction of a homogeneous and informative in vitro profiling database for anticipating the clinical effects of drugs / Nicolas Froloff ... [et al.].