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Translational animal models in drug discovery and development /
Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics,...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
[Place of publication not identified] :
Bentham Science Publishers,
2012.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |z 9781608055913 | ||
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| 245 | 0 | 0 | |a Translational animal models in drug discovery and development / |c editor Xinkang Wang. |
| 260 | |a [Place of publication not identified] : |b Bentham Science Publishers, |c 2012. | ||
| 300 | |a 1 online resource (viii, 275 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Index. | |
| 520 | |a Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics, physiology, anatomy, gene expression, heterogeneity of disease conditions, etc.), not all the preclinical models are able to represent the pathophysiological conditions in human diseases. Therefore, partly due to the lack of congruency between animal and human disease models, several proposed therap. | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Animal models in research. | |
| 650 | 0 | |a Medicine |x Research. | |
| 650 | 6 | |a Modèles animaux dans la recherche. | |
| 650 | 6 | |a Médecine |x Recherche. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
| 650 | 7 | |a Animal models in research. |2 fast |0 (OCoLC)fst00809302 | |
| 650 | 7 | |a Medicine |x Research. |2 fast |0 (OCoLC)fst01015059 | |
| 700 | 1 | |a Wang, Xinkang. | |
| 776 | 0 | 8 | |i Print version: |a Wang, Xinkang. |t Translational Animal Models in Drug Discovery and Development. |d Sharjah : Bentham Science Publishers, ©2012 |z 9781608055913 |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=500723 |z Texto completo |
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