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Targeted therapies in breast cancer /
The development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of brea...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford ; New York :
Oxford University Press,
©2011.
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| Colección: | Oxford American pocket notes.
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| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | The development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of breast cancer, such as trastuzamab (Herceptin, targeting HER-2 positive tumors) and lapatinib (Tykerb, targeting tumors with mutated/overexpressed EGFR 1 and 2). Other agents specifically targeting the estrogen receptor, the aromatose pathway and microtubule dynamics, fulvestrant (Faslodex, targeting th. |
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| Descripción Física: | 1 online resource (54 pages) : illustrations |
| Bibliografía: | Includes bibliographical references. |
| ISBN: | 9780199749751 0199749752 1280699094 9781280699092 9786613676061 6613676063 |