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Critical reviews of oxidative stress and aging : advances in basic science, diagnostics and intervention /

This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Cutler, Richard G., Rodriguez, Henry, 1963-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore ; River Edge, NJ : World Scientific Pub., ©2003.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Vol. 1. Section 1. Historical perspectives. ch. 1. Metabolic rate, free radicals and aging / R.G. Allen and Arthur K. Balin
  • Section 2. Free radical chemistry and biology. ch. 2. Spin-trapping methods for detecting superoxide and hydroxyl free radicals in vitro and in vivo / Garry R. Buettner and Ronald P. Mason
  • ch. 3. Peroxyl and alkoxyl radical mediated DNA damage / John Termini
  • ch. 4. Nitric oxide, peroxynitrite and ageing / Joseph S. Beckman
  • Section 3. Redox regulation and cell signaling. ch. 5. Thioredoxin-dependent redox regulation
  • implication in aging and neurological diseases / Itaro Hattori ... [et al.]
  • ch. 6. Redox regulation of genes and cell function / Arne Holmgren
  • ch. 7. Oxidative stress and signal transduction pathway of redox sensor proteins: clinical applications and novel therapeutics / Toshifumi Tetsuka and Takashi Okamoto
  • Section 4. Measurement of oxidative stress: technology, biomarkers and applications. Nucleic acid damage. ch. 8. Measuring oxidative stress and interpreting its clinical relevance for humans / Roy G. Cutler and Mark P. Mattson
  • ch. 9. Oxidative damage to DNA: mechanisms of product formation and measurement by mass spectrometric techniques / Miral Dizdaroglu, Pawel Jaruga and Henry Rodriguez
  • ch. 10. HPLC-MS/MS measurement of oxidative base damage to isolated and cellular DNA / T. Douki ... [et al.]
  • ch. 11. The use of HPLC/EC for measurements of oxidative DNA damage / Mikhail B. Bogdanov, Wayne R. Matson and Ian N. Acworth
  • ch. 12. Analysis of 8-hydroxyguanine in DNA and its repair / Takeshi Hirano and Hiroshi Kasai
  • ch. 13. HPLC-ECD, HPLC-MS/MS (urinary biomarkers) / H.E. Poulsen ... [et al.]
  • ch. 14. Mapping oxidative damage to DNA at nucleotide resolution in mammalian cells / Timothy R. O'Connor ... [et al.]
  • ch. 15. Immunochemical detection of oxidative DNA damage / Marcus S. Cooke and Joseph Lunec
  • ch. 16. Postlabelling detection of oxidative DNA damage / Michael N. Routledge and George D.D. Jones
  • ch. 17. The comet assay: protective effects of dietary antioxidants against oxidative DNA damage measured using alkaline single cell gel electrophoresis / Susan J. Duthie
  • Protein damage. ch. 18. Protein oxidation assays / Guohua Cao
  • ch. 19. Effect of oxidative stress on protein synthesis / Antonio Ayala and Alberto Machado
  • ch. 20. Biological implications of protein oxidation / Sataro Goto, Zsolt Radák and Ryoya Takahashi
  • ch. 21. Application of protein chip array technology for the detection of biomarkers of oxidative stress / Charlotte H. Clarke, Scot R. Weinberger and Mark S.F. Clarke
  • Lipid damage. ch. 22. Quantification of isoprostanes as an index of oxidant stress status In vivo / Jason D. Morrow ... [et al.]
  • ch. 23. Analysis of phospholipid oxidation by electrospray mass spectrometry / Corinne M. Spickett
  • Carbohydrate damage. ch. 24. Glycoxidative and carbonyl stress in aging and age-related diseases / Vincent M. Monnier ... [et al.].
  • Mitochondrial damage. ch. 25. Mitochondrial mutations in vertebrate aging / Aubrey D.N.J. de Grey
  • ch. 26. Mitochondria, oxidative stress and mitochondrial diseases / Keshav K. Singh, Britt Luccy and Steven J. Zullo
  • Standards for oxidative stress measurements. ch. 27. Oxidative DNA damage biomarkers: a need for quality controls / Andrew R. Collins
  • Section 5. Dietary antioxidants. ch. 28. Dietary antioxidants
  • human studies overview / Paul Milbury and Jeffrey B. Blumberg
  • ch. 29. Current status of the potential role of flavonoids in neuroprotection / Hagen Schroeter, Jeremy P.E. Spencer and Catherine Rice-Evans
  • ch. 30. Neurological aging and nutritional intervention / Barbara Shukitt-Hale, Kuresh A. Youdim and James A. Joseph
  • ch. 31. Comparative study on antioxidant activity against lipid peroxidation / Etsuo Niki and Noriko Noguchi
  • ch. 32. [symbol]-tocopherol: beyond the antioxidant dogma / Theresa Visarius and Angelo Azzi
  • ch. 33. [symbol]-tocopherol, the neglected form of vitamin E: new functions, new interest / Qing Jiang ... [et al.]
  • ch. 34. Ascorbic acid DNA damage and repair / Joseph Lunec
  • ch. 35. Carotenoids and oxidative stress / Norman I. Krinsky
  • ch. 36. Functional foods / Toshihiko Osawa
  • ch. 37. Nutrition and phase II reactions
  • the role of glutathione / Tammy M. Bray and Jun Li
  • ch. 38. Oligomeric proanthocyanidins in human health and disease prevention / Debasis Bagchi and Harry G. Preuss
  • ch. 39. Effects of antioxidant vitamins C and E on gene expression in the vasculature / Helen R. Griffiths and S.J. Rayment
  • Section 6. Endogenous antioxidants and repair. ch. 40. Oxidative defense mechanisms / Cheryl Y. Teoh and Kelvin J.A. Davies
  • ch. 41. Heme oxygenase: its regulation and role / Herbert L. Bonkovsky and Kimberly K. Elbirt
  • ch. 42. Metallothioneins / Y. James Kang
  • ch. 43. Human genomic DNA repair enzymes / Timothy R. O'Connor
  • ch. 44. DNA repair in mammalian mitochondria / Nadja C. Souza-Pinto and Vilhelm Bohr
  • ch. 45. [symbol]-lipoic acid / Chandan K. Sen, Savita Khanna and Sashwati Roy
  • ch. 46. Coenzyme Q10 prevents DNA oxidation and enhances recovery from oxidative damage / Renata Alleva
  • ch. 47. In vivo assessment of antioxidant status / Mohsen Meydani and Ligia Zubik
  • Vol. 2. Section 7. Epidemiology and intervention studies. ch. 48. Epidemiology of antioxidants in cancer and cardiovascular disease / L. Stephen Coles
  • ch. 49. Oxidative stress and antioxidant intervention / Freya Q. Schafer, Eric E. Kelley and Garry R. Buettner
  • ch. 50. Oxidative stress in human populations / Gladys Block ... [et al.].
  • Section 8. Oxidative stress related diseases. ch. 51. Oxidative stress related diseases
  • overview / Joe M. McCord
  • ch. 52. Role of oxidative stress and other novel risk factors in cardiovascular disease / Peter Reaven
  • ch 53. Overview of oxidative stress and cancer / Steven A. Akman
  • ch. 54. Oxidative stress and skin cancer / Arthur K. Balin and R.G. Allen
  • ch. 55. Modification of endogenous antioxidant enzymes in the brain as well as extra-brain tissues by propargylamines: is it related to the lifeprolonging effect of (-)deprenyl? / Kenichi Kitani ... [et al.]
  • ch. 56. Oxidative stress and age-related macular degeneration / Jiyang Cai, Paul Sternberg, Jr. and Dean P. Jones
  • ch. 57. Preeclampsia and antioxidants / Rhoda Wilson
  • ch. 58. Iron regulation, hemochromatosis and cancer / Shinya Toyokuni ... [et al.]
  • Section 9. Aging and oxidative stress. ch. 59. Aging and oxidative stress in transgenic mice / Holly Van Remmen ... [et al.]
  • ch. 60. Caloric restriction, aging and oxidative stress / Kevin C. Kregel
  • ch. 61. Hormones and oxidative stress / Holly M. Brown-Borg and S. Mitchell Harmon
  • ch. 62. Exercise / Helaine M. Alessio
  • Section 10. Evolutionary comparative biology of aging and longevity. ch. 63. Evolutionary basis of human aging / Thomas B.L. Kirkwood
  • ch. 64. Genetic stability, dysdifferentiation, and longevity determinant genes / Richard G. Cutler
  • ch. 65. The genetics of yeast aging: pathways and processes / S. Michal Jazwinski
  • ch. 66. Oxidative stress and longevity determinant genes of drosophila / Robert Arking
  • Section 11. Longevity determinant genes and oxidative stress. ch. 67. Toward a unified theory of aging
  • what mammals can learn from worms and other ephemeral creatures / Robert J. Shmookler Reis
  • ch. 68. Mouse models and longevity / Marco Giorgio and Pier Giuseppe Pelicci
  • ch. 69. Oxidative stress, DNA repair and centenarian survival / Richard Marcotte and Eugenia Wang.
  • Section 12. Non-invasive assessment of oxidative stress and therapeutic intervention. ch. 70. Strategies for controlling oxidative stress: protection against peroxynitrite and hydroperoxides by selenoproteins and selenoorganic compounds / Helmut Sies and Gavin E. Arteel
  • ch. 71. Salen manganese complexes, combined superoxide dismutase/catalase mimetics, demonstrate potential for treating neurodegenerative and other age-associated diseases / Susan R. Doctrow ... [et al.]
  • ch. 72. Glutathione peroxidase mimics / Timothy C. Rodell
  • ch. 73. Nutritional approaches to reducing oxidative stress / Bryant Villeponteau
  • ch. 74. UV-DNA repair enzymes in liposomes / Daniel Yarosh
  • ch. 75. Mitochondrial dysfunction in aging and disease: development of therapeutic strategies / James A. Dykens ... [et al.]
  • ch. 76. Nitric oxide-blocking therapeutics / Ching-San (Monte) Lai and Norman K. Orida
  • ch. 77. Nitric oxide and mammalian aging: "surplus" and "deficit" as the two faces of a pharmaceutical currency for nitric oxide-modulator drugs / David R. Janero
  • ch. 78. Genechips for age/stress-related gene expression and analysis / Chris Seidel and Ralph M. Sinibaldi
  • Section 13. Future trends in health care. ch. 79. Preventive medicine and health care reimbursement: a necessary but not sufficient condition for wider access to preventive health services / Tali Arik
  • ch. 80. Tissue engineering / Hidetomi Terai, Alexander Sevy and Joseph P. Vacanti
  • ch. 81. Database analysis of human intervention studies (The Kronos Longitudinal Study of Aging and Anti-aging Interventions) / Christopher B. Heward
  • ch. 82. Funding trends and possibilities in oxidative stress and aging research / Huber R. Warner and Bradley Wise
  • Section 14. Human life extension. ch. 83. The ethics of longevity: should we extend the healthy maximum lifespan? / Michael Fossel
  • ch. 84. Advisability of human life span extension: economic considerations / Henry Rodriguez and Dwayne A. Banks.