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The ABC transporters of human physiology and disease : genetics and biochemistry of ATP binding cassette transporters /

ATP Binding Cassette (ABC) transporters are a family of integral membrane proteins present in all cells of all species of archaea, eubacteria and eukaryota. The vast majority of these proteins control the transport across cellular membranes of molecules ranging from small ions to drugs, lipids and p...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Linton, Kenneth J., Holland, I. B.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hackensack, N.J. Singapore ; London : World Scientific, 2011.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Ch. 1. General introduction, structure and likely mechanism of action of ABC transport proteins / Kenneth J. Linton, Joseph K. Zolnerciks and Lutz Schmitt
  • ch. 2. ABCA1-mediated HDL formation: mechanism and regulation / Kohjiro Nagao [and others]
  • ch. 3. Bile formation and the enterohepatic circulation / Peter H. Dixon and Catherine Williamson
  • ch. 4. ABCB1 and ABCG2: deciphering the role of human efflux proteins in cellular and tissue permeability / Marcos M. Pires [and others]
  • ch. 5. ABCA4 and its role in the visual cycle and inherited retinal degenerative diseases / Robert S. Molday and Laurie L. Molday
  • ch. 6. The role of the antigen translocation machinery TAP in adaptive immunity / Daphne Nikles and Robert Tampe
  • ch. 7. The ABCs of mitochondrial metabolic disorders / Yu Fukuda [and others]
  • ch. 8. The role of ABCC family members in the disposition of endogenous compounds and drugs / Jorg Konig, Martin F. Fromm and Hartmut Glaeser
  • ch. 9. ABC transporter mutations in heritable skin diseases: the ABCC6 and ABCA12 genes / Qiaoli Li, Qiujie Jiang and Jouni Uitto
  • ch. 10. CFTR: understanding the cause and influencing the outcome of a major genetic disease / Tamas Hegedus, Martina Gentzsch and John R. Riordan
  • ch. 11. ABCC8: physiology and pathology / David Ortiz [and others]
  • ch. 12. The ABCD subfamily: peroxisomal transporters in health and disease / Aurora Pujol and Patrick Aubourg
  • ch. 13. ABCG5/8 and its role in sterol homeostasis / Ronald P.J. Oude Elferink and Coen C. Paulusma
  • ch. 14. Hot topics, recent advances and novel approaches for clinical intervention / Irwin M. Arias [and others].