Structure-activity relationship studies in drug development by NMR spectroscopy. [Volume 1] /

NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parameters which are highly sensitive to the exact...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rahman, Atta-ur-, 1942-, Choudhary, M. Iqbal
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Saif Zone, Sharjah, United Arab Emirates] : Bentham Science Publishers, [2011]
Colección:Structure-activity relationship studies in drug development by NMR spectroscopy, v. 1
Temas:
Nuclear magnetic resonance spectroscopy.
Drugs > Design.
Magnetic Resonance Spectroscopy
Drug Design
Spectroscopie de la résonance magnétique nucléaire.
Médicaments > Conception.
MEDICAL > Drug Guides.
MEDICAL > Nursing > Pharmacology.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
Drugs > Design
Nuclear magnetic resonance spectroscopy
Acceso en línea:Texto completo
Descripción
Sumario:NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parameters which are highly sensitive to the exact environment of the molecules, and therefore yield information about whether a small molecule (candidate compound) binds to a target protein (receptor) or to other macromolecules. These NMR parameters are also used to exactly map the part of the macromolecular target to which the ligand is bound. Spe.
Notas:Cover title.
Descripción Física:1 online resource (iv, 214 pages) : illustrations (some color).
Bibliografía:Includes bibliographical references and index.
ISBN:9781608051649
1608051641
ISSN:2210-2701 ;

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