The SV40 replicon model for analysis of anticancer drugs /

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantag...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Snapka, Robert M., 1947-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [San Diego, Calif.] : Austin, TX : Academic Press ; R.G. Landes, ©1996.
Colección:Molecular biology intelligence unit (Unnumbered)
Temas:
SV40 (Virus)
Viral genetics.
Antineoplastic agents > Research > Methodology.
DNA-drug interactions.
Simian virus 40 > drug effects
Simian virus 40 > genetics
DNA Replication > drug effects
Models, Genetic
Simian virus 40
Virus SV 40.
Génétique virale.
Anticancéreux > Recherche > Méthodologie.
Interactions ADN-médicament.
MEDICAL > Oncology.
HEALTH & FITNESS > Diseases > Cancer.
DNA-drug interactions
Viral genetics
Arzneimittelentwicklung
Arzneimittelwechselwirkung
Cytostatikum
Simian Sarkomvirus
DNS
Repliken.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; The SV40 Replicon Model for Analysis of Anticancer Drugs; Copyright Page; Contents; Chapter 1. Papovavirus Models for Mammalian Replicons; Chapter 2. Analysis of SV40 DNA Replication Intermediates; Chapter 3. Catastrophic Failure of DNA Replication Forks: Structural and Recombinational Pathways; Chapter 4. Topoisomerase II and Termination of DNA Replication; Chapter 5. DNA Damaging Agents; Chapter 6. Drug Discovery and Evaluation with SV40; Chapter 7. SV40 In Vitro DNA Replication: A Potential Model For Studying Anticancer Drug Action.

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