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The SV40 replicon model for analysis of anticancer drugs /

This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantag...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Snapka, Robert M., 1947-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [San Diego, Calif.] : Austin, TX : Academic Press ; R.G. Landes, ©1996.
Colección:Molecular biology intelligence unit (Unnumbered)
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Snapka, Robert M.,  |d 1947- 
245 1 4 |a The SV40 replicon model for analysis of anticancer drugs /  |c Robert M. Snapka. 
260 |a [San Diego, Calif.] :  |b Academic Press ;  |a Austin, TX :  |b R.G. Landes,  |c ©1996. 
300 |a 1 online resource (193 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Molecular biology intelligence unit 
504 |a Includes bibliographical references and index. 
505 0 |a Front Cover; The SV40 Replicon Model for Analysis of Anticancer Drugs; Copyright Page; Contents; Chapter 1. Papovavirus Models for Mammalian Replicons; Chapter 2. Analysis of SV40 DNA Replication Intermediates; Chapter 3. Catastrophic Failure of DNA Replication Forks: Structural and Recombinational Pathways; Chapter 4. Topoisomerase II and Termination of DNA Replication; Chapter 5. DNA Damaging Agents; Chapter 6. Drug Discovery and Evaluation with SV40; Chapter 7. SV40 In Vitro DNA Replication: A Potential Model For Studying Anticancer Drug Action. 
520 |a This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. 
588 0 |a Print version record. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a SV40 (Virus) 
650 0 |a Viral genetics. 
650 0 |a Antineoplastic agents  |x Research  |x Methodology. 
650 0 |a DNA-drug interactions. 
650 1 2 |a Simian virus 40  |x drug effects 
650 1 2 |a Simian virus 40  |x genetics 
650 2 2 |a DNA Replication  |x drug effects 
650 2 2 |a Models, Genetic 
650 2 |a Simian virus 40 
650 6 |a Virus SV 40. 
650 6 |a Génétique virale. 
650 6 |a Anticancéreux  |x Recherche  |x Méthodologie. 
650 6 |a Interactions ADN-médicament. 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Cancer.  |2 bisacsh 
650 7 |a DNA-drug interactions  |2 fast 
650 7 |a SV40 (Virus)  |2 fast 
650 7 |a Viral genetics  |2 fast 
650 7 |a Arzneimittelentwicklung  |2 gnd 
650 7 |a Arzneimittelwechselwirkung  |2 gnd 
650 7 |a Cytostatikum  |2 gnd 
650 7 |a Simian Sarkomvirus  |2 gnd 
650 7 |a DNS  |2 gnd 
655 7 |a Repliken.  |2 swd 
776 0 8 |i Print version:  |a Snapka, Robert M., 1947-  |t SV40 replicon model for analysis of anticancer drugs.  |d [San Diego, Calif.] : Academic Press ; Austin, TX : R.G. Landes, ©1996  |w (DLC) 96000579  |w (OCoLC)34121051 
830 0 |a Molecular biology intelligence unit (Unnumbered) 
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