MicroRNAs in development and cancer /

Mostrar otras versiones (1)

"MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development,...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Slack, Frank J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Singapore : Imperial College Press ; World Scientific [distributor], ©2011.
Colección:Molecular medicine and medicinal chemistry ; v. 1.
Temas:
Small interfering RNA.
Cancer.
MicroRNA.
Tumor markers.
Genetic regulation.
MicroRNAs
Neoplasms > genetics
Neoplasms > therapy
Biomarkers, Tumor
Gene Expression Regulation
RNA, Small Interfering
Neoplasms
Petits ARN interférents.
MicroARN.
Marqueurs tumoraux.
Régulation génétique.
MEDICAL > Oncology.
Tumor markers
MicroRNA
Genetic regulation
Cancer
Small interfering RNA
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction to gene regulation by small RNAs
  • The emerging non-coding RNA world
  • MicroRNAs in C. elegans development
  • MicroRNAs in mammalian development
  • MicroRNAs in hematopoietic development
  • MicroRNAs function as tumor suppressor genes and oncogenes
  • Simultaneous detection of primary, precursor and mature microRNAs by qPCR
  • Single nucleotide polymorphisms in microRNAs and microRNA binding sites with roles in cancer
  • MicroRNAs as potential diagnostics and therapeutics
  • MicroRNA target prediction
  • Non-coding RNAs in cancer: the other part of the story.

Ejemplares similares