Cargando…

MicroRNAs in development and cancer /

"MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development,...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Slack, Frank J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Singapore : Imperial College Press ; World Scientific [distributor], ©2011.
Colección:Molecular medicine and medicinal chemistry ; v. 1.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000 a 4500
001 EBSCO_ocn738434150
003 OCoLC
005 20231017213018.0
006 m o d
007 cr cnu---unuuu
008 110705s2011 enka ob 001 0 eng d
040 |a N$T  |b eng  |e pn  |c N$T  |d EBLCP  |d E7B  |d CDX  |d OCLCQ  |d YDXCP  |d OCLCQ  |d OCLCA  |d OCLCF  |d DEBSZ  |d OCLCQ  |d NLGGC  |d OCLCQ  |d D6H  |d OCLCQ  |d OCLCO  |d LOA  |d OCLCA  |d AGLDB  |d TOA  |d OCLCO  |d MOR  |d PIFAG  |d ZCU  |d OCLCO  |d MERUC  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCA  |d U3W  |d OCLCA  |d STF  |d WRM  |d OCLCQ  |d VTS  |d NRAMU  |d ICG  |d VT2  |d TOF  |d OCLCO  |d AU@  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCA  |d WYU  |d TKN  |d OCLCO  |d DKC  |d OCLCO  |d OCLCQ  |d M8D  |d UKAHL  |d OCLCO  |d UX1  |d OL$  |d OCLCQ  |d OCLCA  |d LEAUB  |d OCLCA  |d UKCRE  |d VLY  |d AJS  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCL  |d OCLCO 
016 7 |a 101561909  |2 DNLM 
016 7 |a 015829358  |2 Uk 
019 |a 961515493  |a 962699302  |a 966253940  |a 988509203  |a 992116780  |a 1037763161  |a 1038585275  |a 1045614782  |a 1055349028  |a 1062885478  |a 1086436982  |a 1153475630  |a 1162463879  |a 1228601833  |a 1241894827  |a 1290056175  |a 1300632361 
020 |a 9781848163676  |q (electronic bk.) 
020 |a 1848163673  |q (electronic bk.) 
020 |a 1283143321 
020 |a 9781283143325 
020 |a 9786613143327 
020 |a 6613143324 
020 |z 9781848163669 
020 |z 1848163665 
029 1 |a AU@  |b 000047752791 
029 1 |a AU@  |b 000050968205 
029 1 |a AU@  |b 000051395121 
029 1 |a AU@  |b 000058165531 
029 1 |a DEBBG  |b BV044156389 
029 1 |a DEBSZ  |b 397097476 
029 1 |a DEBSZ  |b 421584084 
029 1 |a DEBSZ  |b 456484078 
029 1 |a HEBIS  |b 286063565 
029 1 |a NZ1  |b 14167170 
035 |a (OCoLC)738434150  |z (OCoLC)961515493  |z (OCoLC)962699302  |z (OCoLC)966253940  |z (OCoLC)988509203  |z (OCoLC)992116780  |z (OCoLC)1037763161  |z (OCoLC)1038585275  |z (OCoLC)1045614782  |z (OCoLC)1055349028  |z (OCoLC)1062885478  |z (OCoLC)1086436982  |z (OCoLC)1153475630  |z (OCoLC)1162463879  |z (OCoLC)1228601833  |z (OCoLC)1241894827  |z (OCoLC)1290056175  |z (OCoLC)1300632361 
050 4 |a QP623  |b .M535 2011eb 
060 4 |a 2011 F-738 
060 4 |a QU 58.7 
072 7 |a MED  |x 062000  |2 bisacsh 
082 0 4 |a 616.992  |2 22 
049 |a UAMI 
245 0 0 |a MicroRNAs in development and cancer /  |c editor Frank J. Slack. 
260 |a London :  |b Imperial College Press ;  |a Singapore :  |b World Scientific [distributor],  |c ©2011. 
300 |a 1 online resource (xv, 282 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Molecular medicine and medicinal chemistry ;  |v v. 1 
504 |a Includes bibliographical references and index. 
505 0 |a Introduction to gene regulation by small RNAs -- The emerging non-coding RNA world -- MicroRNAs in C. elegans development -- MicroRNAs in mammalian development -- MicroRNAs in hematopoietic development -- MicroRNAs function as tumor suppressor genes and oncogenes -- Simultaneous detection of primary, precursor and mature microRNAs by qPCR -- Single nucleotide polymorphisms in microRNAs and microRNA binding sites with roles in cancer -- MicroRNAs as potential diagnostics and therapeutics -- MicroRNA target prediction -- Non-coding RNAs in cancer: the other part of the story. 
520 |a "MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--Page 4 of cover 
588 0 |a Print version record. 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Small interfering RNA. 
650 0 |a Cancer. 
650 0 |a MicroRNA. 
650 0 |a Tumor markers. 
650 0 |a Genetic regulation. 
650 2 |a MicroRNAs 
650 2 |a Neoplasms  |x genetics 
650 2 |a Neoplasms  |x therapy 
650 2 |a Biomarkers, Tumor 
650 2 2 |a Gene Expression Regulation 
650 2 |a RNA, Small Interfering 
650 2 |a Neoplasms 
650 6 |a Petits ARN interférents. 
650 6 |a Cancer. 
650 6 |a MicroARN. 
650 6 |a Marqueurs tumoraux. 
650 6 |a Régulation génétique. 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
650 7 |a Tumor markers  |2 fast 
650 7 |a MicroRNA  |2 fast 
650 7 |a Genetic regulation  |2 fast 
650 7 |a Cancer  |2 fast 
650 7 |a Small interfering RNA  |2 fast 
700 1 |a Slack, Frank J. 
776 0 8 |i Print version:  |t MicroRNAs in development and cancer.  |d London : Imperial College Press ; Singapore : World Scientific [distributor], ©2011  |z 9781848163669  |w (OCoLC)298781535 
830 0 |a Molecular medicine and medicinal chemistry ;  |v v. 1. 
856 4 0 |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=374850  |z Texto completo 
938 |a Askews and Holts Library Services  |b ASKH  |n AH24682621 
938 |a Coutts Information Services  |b COUT  |n 18078446 
938 |a ProQuest Ebook Central  |b EBLB  |n EBL731333 
938 |a ebrary  |b EBRY  |n ebr10479770 
938 |a EBSCOhost  |b EBSC  |n 374850 
938 |a YBP Library Services  |b YANK  |n 6964853 
994 |a 92  |b IZTAP