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MicroRNAs in development and cancer /
"MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development,...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London : Singapore :
Imperial College Press ; World Scientific [distributor],
©2011.
|
| Colección: | Molecular medicine and medicinal chemistry ;
v. 1. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a MicroRNAs in development and cancer / |c editor Frank J. Slack. |
| 260 | |a London : |b Imperial College Press ; |a Singapore : |b World Scientific [distributor], |c ©2011. | ||
| 300 | |a 1 online resource (xv, 282 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Molecular medicine and medicinal chemistry ; |v v. 1 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Introduction to gene regulation by small RNAs -- The emerging non-coding RNA world -- MicroRNAs in C. elegans development -- MicroRNAs in mammalian development -- MicroRNAs in hematopoietic development -- MicroRNAs function as tumor suppressor genes and oncogenes -- Simultaneous detection of primary, precursor and mature microRNAs by qPCR -- Single nucleotide polymorphisms in microRNAs and microRNA binding sites with roles in cancer -- MicroRNAs as potential diagnostics and therapeutics -- MicroRNA target prediction -- Non-coding RNAs in cancer: the other part of the story. | |
| 520 | |a "MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These 22-nucleotide-long transcripts act to promote or repress cell proliferation, migration and apoptosis during development, all of which are processes that go awry in cancer. Thus, microRNAs have the ability to behave like oncogenes or tumor suppressors. In addition, their small size and molecular properties make them amenable as targets and therapeutics in cancer treatment. This book goes into detail on how microRNAs represent a paradigm shift in thinking about gene regulation during development and disease, and provide the oncologist with a potentially powerful new battery of agents to diagnose and treat cancer."--Page 4 of cover | ||
| 588 | 0 | |a Print version record. | |
| 546 | |a English. | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Small interfering RNA. | |
| 650 | 0 | |a Cancer. | |
| 650 | 0 | |a MicroRNA. | |
| 650 | 0 | |a Tumor markers. | |
| 650 | 0 | |a Genetic regulation. | |
| 650 | 2 | |a MicroRNAs | |
| 650 | 2 | |a Neoplasms |x genetics | |
| 650 | 2 | |a Neoplasms |x therapy | |
| 650 | 2 | |a Biomarkers, Tumor | |
| 650 | 2 | 2 | |a Gene Expression Regulation |
| 650 | 2 | |a RNA, Small Interfering | |
| 650 | 2 | |a Neoplasms | |
| 650 | 6 | |a Petits ARN interférents. | |
| 650 | 6 | |a Cancer. | |
| 650 | 6 | |a MicroARN. | |
| 650 | 6 | |a Marqueurs tumoraux. | |
| 650 | 6 | |a Régulation génétique. | |
| 650 | 7 | |a MEDICAL |x Oncology. |2 bisacsh | |
| 650 | 7 | |a Tumor markers |2 fast | |
| 650 | 7 | |a MicroRNA |2 fast | |
| 650 | 7 | |a Genetic regulation |2 fast | |
| 650 | 7 | |a Cancer |2 fast | |
| 650 | 7 | |a Small interfering RNA |2 fast | |
| 700 | 1 | |a Slack, Frank J. | |
| 776 | 0 | 8 | |i Print version: |t MicroRNAs in development and cancer. |d London : Imperial College Press ; Singapore : World Scientific [distributor], ©2011 |z 9781848163669 |w (OCoLC)298781535 |
| 830 | 0 | |a Molecular medicine and medicinal chemistry ; |v v. 1. | |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=374850 |z Texto completo |
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