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Mitochondria : structure, functions, and dysfunctions /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Svensson, Oliver L.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Nova Science, ©2010.
Colección:Cell biology research progress.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Mitochondria :  |b structure, functions, and dysfunctions /  |c Oliver L. Svensson, editor. 
260 |a New York :  |b Nova Science,  |c ©2010. 
300 |a 1 online resource (xxiii, 1042 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Cell biology research progress 
504 |a Includes bibliographicale references and index. 
588 0 |a Print version record. 
505 0 |a MITOCHONDRIA: STRUCTURE, FUNCTIONS AND DYSFUNCTIONS -- MITOCHONDRIA: STRUCTURE, FUNCTIONS AND DYSFUNCTIONS -- Contents -- Preface -- Mitochondria: The Portrayal of an Executioner -- Abstract -- Introduction -- II. Apoptotic Pathways -- II. A. Extrinsic Pathways -- II. B. Perforin-Granzyme B Pathways -- II. C. Intrinsic Pathways -- II. D. Execution Pathway -- III. Mitochondria and Gateways to Mitochondrial Death -- III. A. Mitochondria and Cell -- III. B. Regulation of Mitochondrial Membrane Permeabilization -- III. B.1. Non-protein mediators -- Calcium 
505 8 |a Lipid and lipid metabolitesSmall molecules -- III. B.2. Protein mediators: Bcl-2 family-intrinsic regulators of cellular life and death -- III. B.2.1. Properties of Bcl-2 family members -- III. B.2.2. Upstream of mitochondria: Activation of BCL-2 family members -- III. B.2.3. Post-translational modifications determine active/inactive conformations -- III. B.2.3.a. Dimerization -- III. B.2.3.b. Translocation -- III. B.2.3.c. Phosphorylation -- III. B.2.3.d. Cleavage -- III. B.2.3.e. Transcription -- III. B.2.4. Pro-apoptotic BCL-2 members as sentinels for cellular damage 
505 8 |a III. C. Characteristics of Apoptotic Membrane PermeabilizationIII. D. Models of Mitochondrial Membrane Permeabilization -- III. D.1. Permeabilization of the inner membrane along with the rupture of the Outer Membrane -- III. D.2. The adenine nucleotide transporter -- III. D.3. BCL-XL and ADP/ATP Exchange -- III. D.4. Selective permeabilization of the Outer Mitochondrial Membrane -- III. D.5. Outer Membrane permeabilization by VDAC -- III. E. Mitochondrial Membrane Permeabilization and Released Factors -- III. E.1. Cytochrome c -- III. E.2. Daiblo/Smac -- III. E.3. HtrA2/Omi 
505 8 |a III. E.4. Procaspase-2 and 9III. E.5. Hsp 10, Hsp60 -- III. E.6. AIF -- III. E.7. Release of Endonuclease G -- III. E.8. Adenylate Kinase 2 -- III. F. Outcome of Mitochondrial Membrane Permeabilization -- III. F.1. Apoptosome -- Active versus inactive apoptosomes -- The role of cytochrome c and dATP in apoptosome assembly and caspase-9 processing -- III. F.2. Breakdown of oxidative phosphorylation -- IV. PTPC Structure and Mitochondrial Permeability Transition- A Final Word -- V. Effects of Mitochondria Membrane Permeabilization 
505 8 |a VI. Afferent Signals Form Other Organelles Inducing MMPVI. A. Nuclear DNA Damage -- VI. A.1. Signals from the “guardian of genomeâ€? to mitochondria -- VI. B. Endoplasmic Reticulum -- VI. C. Lysosomes -- VI. D. Cytosol -- VI. D.1. The ubiquitin/proteasome complex -- VI. D.2. The phosphatidylinositol-3-kinase pathway -- VI. D.3. Apoptosis signal-regulating kinase/mitogen-activated protein kinase -- VI. E. Cytoskeleton -- VII. Apoptosis, Mitochondria and Human Disease -- VII. A. Ischemia/Reperfusion -- VII. B. Aging and Mitochondrial Damage 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Mitochondria. 
650 1 2 |a Mitochondria  |x physiology 
650 2 2 |a Mitochondria  |x metabolism 
650 2 2 |a Mitochondria  |x pathology 
650 2 |a Mitochondria 
650 6 |a Mitochondries. 
650 7 |a SCIENCE  |x Life Sciences  |x Cell Biology.  |2 bisacsh 
650 7 |a Mitochondria  |2 fast 
650 1 7 |a Mitochondriën.  |2 gtt 
650 1 7 |a Pathologische fysiologie.  |2 gtt 
700 1 |a Svensson, Oliver L. 
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