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Protein-protein complexes : analysis, modeling and drug design /

Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Zacharias, Martin
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Singapore ; Hackensack, NJ : Imperial College Press ; Distributed by World Scientific Pub. Co., ©2010.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Protein-protein complexes :  |b analysis, modeling and drug design /  |c edited by Martin Zacharias. 
260 |a London :  |b Imperial College Press ;  |a Singapore ;  |a Hackensack, NJ :  |b Distributed by World Scientific Pub. Co.,  |c ©2010. 
300 |a 1 online resource (ix, 390 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a X-ray study of protein-protein complexes and analysis of interfaces / Joel Janin -- A structural perspective on protein-protein interactions in macromolecular assemblies / Ranjit P. Bahadur -- Energetics of protein-protein interactions / Ilian Jelesarov -- Kinetics of biomacromolecular complex formation: theory and experiment / Georgi V. Pachov, Razif R. Gabdoulline and Rebecca C. Wade -- Evolutionary trace of protein functional determinants / Olivier Lichtarge -- Protein-protein docking / Adrien Saladin and Chantal Prevost -- Data-driven docking: using external information to spark the biomolecular rendez-vous / Adrien S.J. Melquiond and Alexandre M.J.J. Bonvin -- High-resolution protein-protein docking / Nir London and Ora Schueler-Furman -- Scoring and refinement of predicted protein-protein complexes / Martin Zacharias -- Motif-mediated protein interactions and their role in disease / Holger Dinkel and Heinrich Sticht -- Prediction and calculation of protein-protein binding affinities and mutation effects / Sébastien Fiorucci, Serge Antonczak and Jérôme Golebiowski -- Small-molecule inhibitors of protein-protein interactions / Thorsten Berg -- Protein dynamics and drug design: the role of molecular simulations / Giulia Morra, Alessandro Genoni and Giorgio Colombo. 
588 0 |a Print version record. 
520 |a Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge. 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Protein-protein interactions. 
650 0 |a Carrier proteins. 
650 0 |a Proteins  |x Conformation. 
650 2 |a Multiprotein Complexes  |x chemistry 
650 2 |a Protein Interaction Mapping 
650 2 |a Carrier Proteins 
650 2 |a Protein Conformation 
650 6 |a Interactions protéine-protéine. 
650 6 |a Protéines de liaison. 
650 6 |a Protéines  |x Conformation. 
650 7 |a SCIENCE  |x Life Sciences  |x Biochemistry.  |2 bisacsh 
650 7 |a Proteins  |x Conformation.  |2 fast  |0 (OCoLC)fst01079725 
650 7 |a Carrier proteins.  |2 fast  |0 (OCoLC)fst00847934 
650 7 |a Protein-protein interactions.  |2 fast  |0 (OCoLC)fst01079705 
700 1 |a Zacharias, Martin. 
776 0 8 |i Print version:  |t Protein-protein complexes.  |d London : Imperial College Press ; Singapore ; Hackensack, NJ : Distributed by World Scientific Pub. Co., ©2010  |z 9781848163386  |w (OCoLC)619653723 
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