Cargando…

Molecular chaperones and cell signalling /

This book reviews current understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic parad...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Henderson, Brian (Professor), Pockley, A. Graham (Alan Graham), 1960-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, UK ; New York : Cambridge University Press, 2005.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:This book reviews current understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first-and-foremost protein-folding molecules. The current paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described.
Descripción Física:1 online resource (xiv, 330 pages) : illustrations
Bibliografía:Includes bibliographical references and index.
ISBN:9780511345159
0511345151
9780511546310
0511546319