Cargando…
Drug discovery and development for Alzheimer's disease 2000 /
This prestigious volume presents the findings of an international group of academic and biotechnological researchers. Topics range from early detection programs focusing on genetic factors, novel probes for detecting B-amyloid in the living brain, and the use of telephonic screening and MRI's t...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Springer Pub Co.,
©2002.
|
| Colección: | ISOA Annual Investigators Meeting.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | EBSCO_ocn647888734 | ||
| 003 | OCoLC | ||
| 005 | 20231017213018.0 | ||
| 006 | m o d | ||
| 007 | cr un||||a|a|| | ||
| 008 | 100714s2002 nyua ob 101 0 eng d | ||
| 040 | |a OCLCE |b eng |e pn |c OCLCE |d N$T |d IDEBK |d E7B |d OCLCQ |d MERUC |d OCLCQ |d NLGGC |d YDXCP |d EBLCP |d OCLCO |d OCLCQ |d OCLCO |d OCLCQ |d AZK |d TOA |d COCUF |d AGLDB |d MOR |d PIFAG |d ZCU |d OCLCQ |d OCLCO |d OCLCA |d U3W |d OCLCO |d OCLCF |d STF |d VNS |d WRM |d OCLCQ |d VTS |d NRAMU |d ICG |d INT |d REC |d VT2 |d OCLCO |d AU@ |d WYU |d OCLCO |d OCLCA |d OCLCQ |d OCLCO |d DKC |d OCLCQ |d OCLCO |d OCLCA |d OCLCQ |d CEF |d M8D |d UX1 |d HS0 |d OCLCO |d OCLCQ |d OCLCA |d UKCRE |d OCLCQ |d OCLCO |d MHW |d OCLCO |d OCLCA |d OCLCQ | ||
| 019 | |a 298714562 |a 476262739 |a 604807775 |a 646782919 |a 764507194 |a 961487511 |a 962568352 |a 974469750 |a 974510257 |a 988497643 |a 992075565 |a 1002407262 |a 1017997973 |a 1037918190 |a 1038046331 |a 1038678966 |a 1043529799 |a 1045469457 |a 1047951236 |a 1053605745 |a 1054122655 |a 1055350243 |a 1058115591 |a 1064767029 |a 1081291758 |a 1084341994 |a 1096476902 |a 1153560784 |a 1157014748 |a 1157568649 |a 1178683829 |a 1228576583 | ||
| 020 | |a 9780826115348 |q (electronic bk.) | ||
| 020 | |a 0826115349 |q (electronic bk.) | ||
| 020 | |z 082611542X | ||
| 020 | |z 9780826115423 | ||
| 029 | 1 | |a AU@ |b 000051544876 | |
| 029 | 1 | |a DEBBG |b BV043108350 | |
| 029 | 1 | |a DEBBG |b BV044134336 | |
| 029 | 1 | |a DEBSZ |b 422069299 | |
| 029 | 1 | |a GBVCP |b 803314302 | |
| 029 | 1 | |a NZ1 |b 13858630 | |
| 029 | 1 | |a DKDLA |b 820120-katalog:999930901905765 | |
| 029 | 1 | |a AU@ |b 000054174405 | |
| 035 | |a (OCoLC)647888734 |z (OCoLC)298714562 |z (OCoLC)476262739 |z (OCoLC)604807775 |z (OCoLC)646782919 |z (OCoLC)764507194 |z (OCoLC)961487511 |z (OCoLC)962568352 |z (OCoLC)974469750 |z (OCoLC)974510257 |z (OCoLC)988497643 |z (OCoLC)992075565 |z (OCoLC)1002407262 |z (OCoLC)1017997973 |z (OCoLC)1037918190 |z (OCoLC)1038046331 |z (OCoLC)1038678966 |z (OCoLC)1043529799 |z (OCoLC)1045469457 |z (OCoLC)1047951236 |z (OCoLC)1053605745 |z (OCoLC)1054122655 |z (OCoLC)1055350243 |z (OCoLC)1058115591 |z (OCoLC)1064767029 |z (OCoLC)1081291758 |z (OCoLC)1084341994 |z (OCoLC)1096476902 |z (OCoLC)1153560784 |z (OCoLC)1157014748 |z (OCoLC)1157568649 |z (OCoLC)1178683829 |z (OCoLC)1228576583 | ||
| 042 | |a dlr | ||
| 050 | 4 | |a RC523 |b .D78 2002 | |
| 060 | 4 | |a 2002 C-079 | |
| 060 | 4 | |a WT 155 |b A24383 2002 | |
| 072 | 7 | |a HEA |x 039140 |2 bisacsh | |
| 072 | 7 | |a MED |x 056000 |2 bisacsh | |
| 082 | 0 | 4 | |a 616.8/31061 |2 21 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Drug discovery and development for Alzheimer's disease 2000 / |c Howard M. Fillit, Alan W. O'Connell, editors. |
| 246 | 1 | |i At head of title: |a Institute for the Study of Aging | |
| 260 | |a New York : |b Springer Pub Co., |c ©2002. | ||
| 300 | |a 1 online resource (xvi, 280 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file | ||
| 490 | 1 | |a ISOA Annual Investigators Meeting | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a This prestigious volume presents the findings of an international group of academic and biotechnological researchers. Topics range from early detection programs focusing on genetic factors, novel probes for detecting B-amyloid in the living brain, and the use of telephonic screening and MRI's to the diversity of therapeutic areas such as antioxidants, estrogen agonists and various anti-B-amyloid and anti-tangle approaches. The volume is still an indispensable resource for the psychogeriatrician, psychiatrist, clinical investigator, and neurobiologist, and a must for medical libraries. | ||
| 506 | |3 Use copy |f Restrictions unspecified |2 star |5 MiAaHDL | ||
| 533 | |a Electronic reproduction. |b [Place of publication not identified] : |c HathiTrust Digital Library, |d 2010. |5 MiAaHDL | ||
| 538 | |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |u http://purl.oclc.org/DLF/benchrepro0212 |5 MiAaHDL | ||
| 583 | 1 | |a digitized |c 2010 |h HathiTrust Digital Library |l committed to preserve |2 pda |5 MiAaHDL | |
| 505 | 0 | |a 1. The Challenges of Drug Discovery and Drug Development for Cognitive Aging and Alzheimer's Disease / Howard Fillit and Alan O'Connell -- pt. I. Early Detection -- 2. Genetic Correlates of Successful Cognitive Aging / Thomas Perls -- 3. Genetic and Environmental Risk Factors for Alzheimer's Disease in Arabs Residing in Israel / Robert P. Friedland, Amos Korczyn and Lindsay Farrer -- 4. Telephonic Screening of Mental Status: A Feasibility Study in a Managed Care Clinic / David Knopman, Thomas Vonsternberg and Jim Haefemeyer -- 5. Use of Brain MRI Volumetric Analysis in a Mild Cognitive Impairment Trial to Delay the Diagnosis of Alzheimer's Disease / Michael Grundman, Drahomira Sencakova and Clifford R. Jack, Jr. / [and others] -- 6. Hippocampal Volume Assessment in Mild Cognitive Impairment / Michael S. Mega, Paul M. Thompson and Arthur W. Toga / [and others] -- 7. Brain Imaging Surrogate Markers for Detection and Prevention of Cognitive Aging and Alzheimer's Disease / Gary W. Small -- 8. Novel [beta]-Amyloid Probes / Mei-Ping Kung, Zhi-Ping Zhuang and Catherine Hou / [and others] -- 9. Early Clinical and Biological Manifestations of Alzheimer's Disease: Implications for Screening and Treatment / Richard C. Mohs, Deborah Marin and Vahram Haroutunian -- pt. II. Drug Discovery -- 10. Identification of Brain-Expressed ABC Transporters That May Mediate Detachment of [beta]-Amyloid From Biological Membranes / Peter B. Reiner and Stephane Le Bihan -- 11. Targeting an RNA Structure in the Amyloid Precursor Protein Gene as a New Therapeutic Strategy for Alzheimer's Disease / Jack T. Rogers -- 12. Novel Tricyclic Pyrone Compounds Prevent Intracellular APP C99-Induced Cell Death / Lee-Way Jin, Duy H. Hua and Feng-Shiun Shie / [and others] -- 13. Novel Glycosaminoglycans as Antiamyloid Agents / Robert Kisilevsky and Walter A. Szarek -- 14. Strategies for Inhibiting Alzheimer's [gamma]-Secretase / Michael S. Wolfe -- 15. Phosphorylations of Tau and APP as Targets for Drug Discovery / John DeBernardis, Dan Kerkman and Cintia Vianna / [and others] -- 16. Estrogen and ApoE: Drug Discovery Implications / Jonathan D. Smith and Justine A. Levin -- 17. Structure-Based Functional Design of Agonists and Antagonists for AMPA-Subtype Glutamate Receptors / Ming-Ming Zhou, Harel Weinstein and Diomedes E. Logothetis / [and others] -- 18. Alzheimer's Therapeutics: Neurotrophin Small Molecule Mimetics / Stephen M. Massa, You-Mei Xie and Frank M. Longo -- pt. III. Drug Development -- Preclinical -- 19. Antioxidants in the Treatment of Alzheimer's Disease: Breakthrough Potential of Indole-3-Propionic Acid / Daniel G. Chain, Douglas Galasko and Eyal Neria / [and others] -- 20. AF150(S) and AF267B: M1 Muscarinic Agonists for Treatment and as Disease-Modifying Agents in Alzheimer's and Related Diseases / A. Fisher, Z. Pittel and R. Brandeis / [and others] -- 21. ABS-205: Effects on Cognition in Mature and Aged Rats / Ciaran M. Regan -- 22. Calpain Inhibitors: A Treatment of Alzheimer's Disease / Ottavio Arancio -- 23. Femtomolar-Acting Neuroprotective Peptides: Application for Inhibition of Alzheimer's Disease / Illana Gozes, Sharon Furman and Ruth A. Steingart / [and others] -- pt. IV. Drug Development -- Clinical -- 24. A Phase I Clinical Study of Ex Vivo Nerve Growth Factor Gene Therapy for Alzheimer's Disease / Mark H. Tuszynski -- 25. Lowering Homocysteine Levels in Patients With Alzheimer's Disease / Paul Aisen, Mary Sano and Ramon Diaz-Arrastia / [and others] -- 26. Therapeutic Potential of Positive AMPA Receptor Modulators in Mild Cognitive Impairment and Alzheimer's Disease / Steven A. Johnson, Gary Lynch and Gary A. Rogers / [and others] -- 27. The Alzheimer's Disease Atorvastatin Treatment Trial: Scientific Basis and Position on the Use of HMG-CoA Reductase Inhibitors (Statins) That Do or Do Not Cross the Blood-Brain Barrier / D. Larry Sparks, Donald J. Connor and Patrick J. Browne / [and others] -- 28. A Double-Blind, Randomized Investigation of the Effects of Testosterone or Placebo in Male Patients With Mild-to-Moderate Alzheimer's Disease / Bruce Miller -- 29. Estrogen and Cognitive Functioning in Men With Mild Cognitive Impairment / Barbara B. Sherwin and Howard Chertkow. | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Alzheimer's disease |x Chemotherapy |v Congresses. | |
| 650 | 0 | |a Alzheimer's disease |x Chemotherapy |x Evaluation |v Congresses. | |
| 650 | 0 | |a Drugs |x Testing |v Congresses. | |
| 650 | 1 | 2 | |a Alzheimer Disease |x diagnosis |
| 650 | 1 | 2 | |a Alzheimer Disease |x drug therapy |
| 650 | 2 | 2 | |a Dementia |x drug therapy |
| 650 | 6 | |a Maladie d'Alzheimer |x Chimiothérapie |v Congrès. | |
| 650 | 6 | |a Maladie d'Alzheimer |x Chimiothérapie |x Évaluation |v Congrès. | |
| 650 | 6 | |a Médicaments |x Essais cliniques |v Congrès. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Alzheimer's & Dementia. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Neurology. |2 bisacsh | |
| 650 | 7 | |a Alzheimer's disease |x Chemotherapy. |2 fast |0 (OCoLC)fst00806536 | |
| 650 | 7 | |a Drugs |x Testing. |2 fast |0 (OCoLC)fst00898940 | |
| 650 | 7 | |a Alzheimerkrankheit |2 gnd | |
| 650 | 7 | |a Pharmakotherapie |2 gnd | |
| 650 | 7 | |a Nootropikum |2 gnd | |
| 650 | 7 | |a Pharmakologie |2 gnd | |
| 655 | 2 | |a Congress | |
| 655 | 7 | |a Conference papers and proceedings. |2 fast |0 (OCoLC)fst01423772 | |
| 655 | 7 | |a Conference papers and proceedings. |2 lcgft | |
| 655 | 7 | |a Actes de congrès. |2 rvmgf | |
| 700 | 1 | |a Fillit, Howard. | |
| 700 | 1 | |a O'Connell, Alan W. | |
| 710 | 2 | |a Institute for the Study of Aging. | |
| 776 | 0 | 8 | |i Print version: |t Drug discovery and development for Alzheimer's disease 2000. |d New York : Springer Pub Co., ©2002 |w (DLC) 2001049760 |w (OCoLC)48046242 |
| 830 | 0 | |a ISOA Annual Investigators Meeting. | |
| 856 | 4 | 0 | |u https://ebsco.uam.elogim.com/login.aspx?direct=true&scope=site&db=nlebk&AN=246181 |z Texto completo |
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL423414 | ||
| 938 | |a ebrary |b EBRY |n ebr10265604 | ||
| 938 | |a EBSCOhost |b EBSC |n 246181 | ||
| 938 | |a ProQuest MyiLibrary Digital eBook Collection |b IDEB |n 180665 | ||
| 938 | |a YBP Library Services |b YANK |n 2947954 | ||
| 994 | |a 92 |b IZTAP | ||