DNA microarray technology and data analysis in cancer research /

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DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Li, Shaoguang
Otros Autores: Li, Dongguang
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore ; Hackensack, NJ : World Scientific, ©2008.
Temas:
Cancer cells > Growth > Regulation.
DNA microarrays.
Diseases.
Methodology.
Research.
Gene expression.
Science.
Nucleic acid hybridization.
Decision making > Mathematical models.
Genetics > Technique.
Physical sciences.
Genetic Phenomena
Disease
Methods
Sequence Analysis
Oligonucleotide Array Sequence Analysis > methods
Oligonucleotide Array Sequence Analysis
Neoplasms
Data Interpretation, Statistical
Research
Gene Expression
Science
Investigative Techniques
Molecular Probe Techniques
Microarray Analysis
Nucleic Acid Hybridization
Decision Support Techniques
Analytical, Diagnostic and Therapeutic Techniques and Equipment
Genetic Techniques
Microchip Analytical Procedures
Natural Science Disciplines
Chemistry Techniques, Analytical
Phenomena and Processes
Disciplines and Occupations
Cellules cancéreuses > Croissance > Régulation.
Puces à ADN.
Maladies.
Méthodologie.
Recherche.
Expression génique.
Sciences.
Acides nucléiques > Hybridation.
Prise de décision > Modèles mathématiques.
Génétique > Technique.
Sciences physiques.
illness.
disease.
methodology.
research (function)
sciences (philosophy)
physical sciences.
science (modern discipline)
MEDICAL > Oncology.
HEALTH & FITNESS > Diseases > Cancer.
Physical sciences
Nucleic acid hybridization
Methodology
Genetics > Technique
Gene expression
Diseases
Decision making > Mathematical models
Cancer cells > Growth > Regulation
DNA microarrays
Acceso en línea:Texto completo
Descripción
Sumario:DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology.
Descripción Física:1 online resource (xi, 118 pages) : illustrations (some color)
Bibliografía:Includes bibliographical references (pages 105-115) and index.
ISBN:9789812790460
9812790462
1282441248
9781282441248
9786612441240
6612441240

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