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Computational systems bioinformatics : CSB2007 Conference proceedings, volume 6, University of California, San Diego, 13-17 August 2007 /

This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinf...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores Corporativos: Computational Systems Bioinformatics Conference San Diego, Calif., Life Sciences Society
Otros Autores: Markstein, Peter, Xu, Ying, 1960-
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: London : Singapore ; Hackensack, NJ : Imperial College Press ; Distributed by World Scientific, 2007.
Colección:Series on advances in bioinformatics and computational biology.
Temas:
Acceso en línea:Texto completo

MARC

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111 2 |a Computational Systems Bioinformatics Conference  |n (6th :  |d 2007 :  |c San Diego, Calif.) 
245 1 0 |a Computational systems bioinformatics :  |b CSB2007 Conference proceedings, volume 6, University of California, San Diego, 13-17 August 2007 /  |c editors, Peter Markstein, Ying Xu. 
246 3 |a CSB 2007 Conference proceedings 
246 3 0 |a CSB2007 Conference proceedings 
260 |a London :  |b Imperial College Press ;  |a Singapore ;  |a Hackensack, NJ :  |b Distributed by World Scientific,  |c 2007. 
300 |a 1 online resource (xvi, 454 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Series on advances in bioinformatics and computational biology 
490 1 |a Series on Advances in Bioinformatics and Computational Biology ;  |v v.6 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Preface; Committees; Referees; Keynote Address; Quantitative Aspects of Gene Regulation in Bacteria: Amplification. Threshold, and Combinatorial Control Terry Hwa; Whole-Genome Analysis of Dorsal Gradient Thresholds in the Drosophila Embryo Julia ZeitlingeK Rob Zinzen, Dmitri Papatsenko et al.; Invited Talks; Learning Predictive Models of Gene Regulation Christina Leslie; The Phylofacts Phylogenomic Encyclopedias: Structural Phylogenomic Analysis Across the Tree of Life Kimmen Golander; Mapping and Analysis of the Human Interactome Network Kavitha Venkatesan; 1. INTRODUCTION 
505 8 |a Gene-Centered Protein-DNA lnteractome Mapping A.J. Marian WalhoutProteomics; Algorithm for Peptide Sequencing by Tandem Mass Spectrometry Based on Better Preprocessing and Anti-S ymmetric Computational Model Kang Ning and Hon Wai Leong; 1. INTRODUCTION; Preprocessing to remove noisy peaks; The anti-symmetric problem; 2. ANALYSIS OF PROBLEMS AND CURRENT ALGORITHMS; 2.1. General Terminologies; 2.2. Datasets; 2.3. Problems Analysis; 3. NEW COMPUTATIONAL MODELS AND ALGORITHM; 3.1. Preprocessing to remove noisy peaks and introduce pseudo peaks; 3.2. The Anti-symmetric Problem 
505 8 |a 3.3. Novel Peptide Sequencing Algorithm4. EXPERIMENTS; 4.1. Experiment Settings; 4.2. Results; 5. CONCLUSIONS; References; Algorithms for Selecting Breakpoint Locations to Optimize Diversity in Protein Engineering by Site-Directed Protein Recombination Wei Zheng, Xiaoduan Ye, Alan A4 Friedman and Chris Bailey-Kellogg; 1. INTRODUCTION; 2. METHODS; 2.1. Library Diversity; 2.2. Metrics for Breakpoint Selection; 2.3. Dynamic Programming for Breakpoint Selection; 3. RESULTS A N D DISCUSSION; 4. CONCLUSION; ACKNOWLEDGMENTS; References 
505 8 |a An Algorithmic Approach to Automated High-Throughput Identification of Disulfide Connectivity in Proteins Using Tandem Mass Spectrometry Timothy Lee, Rahul Singh, Ten-Yang Yen and Bruce Macher1. INTRODUCTION; 1.1. Comparison of the Proposed Approach with Related Works; 2. THE PROPOSED METHOD; 2.1. Problem Formulation; 2.2. Algorithmic Framework; 2.2.1. Finding the MS spectrum match; 2.2.2. Finding the MS/MS spectrum match; 2.2.3. Finding a perfect matching of maximum weight for a fully connected graph; 2.2.4. Consideration of missed proteolytic cleavages and intra-molecular bonded cysteines 
505 8 |a 2.2.5. Peak finding in the presence of noise2.2.6. Addressing isotopic variation and neutral loss; 2.2.7. Interpretation of peaks given charge state uncertainty; 2.2.8. Overall complexity; 3. EXPERIMENTAL RESULTS; 3.1. Description of the Data and Experimental Procedures; 3.2. Summary of Results; 3.2.1. Analysis of the effect of varying threshold t on results; 3.2.2. Comparison with MS2Assign program; 4. CONCLUSIONS AND DISCUSSION; Acknowledgments; References; Biomedical Application; Cancer Molecular Pattern Discovery by Subspace Consensus Kernel Classification Xiaoxu Hun; 1. INTRODUCTION 
520 |a This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. Abstracts from the keynote addresses and invited talks are also included. The papers not only cover theoretical aspects of bioinformatics but also delve into the application of n. 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Bioinformatics  |v Congresses. 
650 0 |a Biological systems  |x Computer simulation  |v Congresses. 
650 0 |a Biological systems  |x Simulation methods  |v Congresses. 
650 0 |a Computational biology  |v Congresses. 
650 0 |a Systems biology. 
650 1 2 |a Computational Biology 
650 2 2 |a Systems Biology 
650 2 2 |a Models, Genetic 
650 2 2 |a Models, Molecular 
650 6 |a Bio-informatique  |v Congrès. 
650 6 |a Systèmes biologiques  |x Simulation par ordinateur  |v Congrès. 
650 6 |a Systèmes biologiques  |x Méthodes de simulation  |v Congrès. 
650 6 |a Bio-informatique. 
650 6 |a Biologie systémique. 
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650 7 |a Bioinformatics  |2 fast 
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650 7 |a Biological systems  |x Simulation methods  |2 fast 
650 7 |a Computational biology  |2 fast 
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655 7 |a proceedings (reports)  |2 aat 
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655 7 |a Conference papers and proceedings.  |2 lcgft 
655 7 |a Actes de congrès.  |2 rvmgf 
700 1 |a Markstein, Peter. 
700 1 |a Xu, Ying,  |d 1960- 
710 2 |a Life Sciences Society. 
776 0 8 |i Print version:  |a Computational Systems Bioinformatics Conference (6th : 2007 : San Diego, Calif.).  |t Computational systems bioinformatics.  |d London : Imperial College Press ; Singapore ; Hackensack, NJ : Distributed by World Scientific, 2007  |w (DLC) 2008295420 
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