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Virtual ADMET Assessment in Target Selection and Maturation.
Today, biologists and medicinal chemists realize that there is a strong relationship between pharmacodynamic (what the drug does to the organism) and pharmacokinetic (what the organism does to the drug) effects. A significant contributing factor to the evolution in drug discovery was the methodologi...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
IOS Press,
2006.
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| Colección: | Solvay Pharmaceuticals Conferences ;
v. 6. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Today, biologists and medicinal chemists realize that there is a strong relationship between pharmacodynamic (what the drug does to the organism) and pharmacokinetic (what the organism does to the drug) effects. A significant contributing factor to the evolution in drug discovery was the methodological and technological revolution with the advent of combinatorial chemistry, high-throughput screening and profiling, and in silico prediction of target-based activity and ADMET (absorption, distribution, metabolism, excretion and toxicity) properties. High-throughput screening and in silico methods. |
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| Descripción Física: | 1 online resource (268 pages) |
| Bibliografía: | Includes bibliographical references and index. |
| ISBN: | 9781433701559 1433701553 9781429467728 142946772X 9781607502197 1607502194 1280810564 9781280810565 9786610810567 6610810567 6000006047 9786000006044 |
| ISSN: | 1566-7685 ; |