Tabla de Contenidos:
  • Front Matter
  • Preface
  • Contents
  • Opening Remarks
  • Introductory Comments on Microbiologic Testing of Laboratory Mice and Rats: Uniformity of Results
  • Development of a Performance Assessment Program for Research Animal Diagnostic Laboratories and Defining Microbiologic Testing Standards
  • Standardization of Rodent Health Surveillance: Regulation Versus Competition
  • Factors Causing Difficulties in Uniformity of Results Among Testing Facilities in Microbiologic Monitoring of Laboratory Animals
  • Necessity of Reexamining the Pathogenicity and Elimination of Parasites in Rats and MiceEmerging (and Reemerging) Viruses of Laboratory Mice and Rats
  • Emerging Infections as a Cause of Concern
  • Emerging Diseases in Mice and Rats
  • Survey of Helicobacter Species in Laboratory Mice and Gerbils in Japan
  • Genetic Evaluation of Outbred Rats
  • Genetic Evaluation of Outbred Rats from the Breederâ€?s Perspective
  • Concept for Establishment of Rat Outbred Global Standard Strains
  • Necessity of Genetic and Microbiologic Quality Network from the Pharmaceutical Industryâ€?s PerspectiveInternational Harmonization of Laboratory Animals
  • Rat Genetics and Toxicology
  • A Phenotype-driven Approach to the Molecular and Functional Analysis of the Mouse Genome
  • Evaluation of Targeted Mutations
  • Defining Behavioral Phenotypes in Transgenic and Knockout Mice
  • Defining Phenotype in Genetically Engineered Mice
  • Development of the Mouse Model Dramatype for Human Clinical Benefit
  • Concluding Remarks
  • Implication of Wild-derived Genes, Mitochondria, and Chromosomes in the Genetic Background of Mouse Models for Diseases and Biologic FunctionsConcluding Comments
  • Concluding Comments
  • Appendix A U.S./Japan Meeting November 15, 1999 Agenda
  • Appendix B Meeting Participants