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Computational systems bioinformatics : CSB2006 conference proceedings, Stanford CA, 14-18 August 2006 /

This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinf...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores Corporativos: Computational Systems Bioinformatics Conference Stanford, Calif., Hewlett-Packard Company, Microsoft Research, Life Sciences Society
Otros Autores: Markstein, Peter, Xu, Ying, 1960-
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: London : Imperial College Press, ©2006.
Colección:Series on advances in bioinformatics and computational biology ; v. 4.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Committees
  • Referees
  • Preface
  • Keynote Addresses. Exploring the ocean's microbes: sequencing the seven seas / Marvin E. Frazier [and others]. Don't know much about philosophy: the confusion over bio-ontologies / Mark A. Musen
  • Invited talks. Biomedical Informatics Research Network (BIRN): building a national collaboratory for bioMedical and brain research / Mark H. Ellisman. Protein network comparative genomics / Trey Ideker. Systems biology in two dimensions: understanding and engineering membranes as dynamical systems / Erik Jakobsson. Bioinformatics at Microsoft Research / Simon Mercer. Movie crunching in biological dynamic imaging / Jean-Christophe Olivo-Marin. Engineering nucleic acid-based molecular sensors for probing and programming cellular systems / Christina D. Smolke. Reactome: a knowledgebase of biological pathways / Lincoln Stein [and others]
  • Structural bioinformatics. Effective optimization algorithms for fragment-assembly based protein structure prediction / Kevin W. DeRonne and George Karypis. Transmembrane helix and topology prediction using hierarchical SVM classifiers and an alternating geometric scoring function / Allan Lo [and others]. Protein fold recognition using the gradient boost algorithm / Feng Jiao [and others]. A graph-based automated NMR backbone resonance sequential assignment / Xiang Wan and Guohui Lin. A data-driven, systematic search algorithm for structure determination of denatured or disordered proteins / Lincong Wang and Bruce Randall Donald. Multiple structure alignment by optimal RMSD implies that the average structure is a consensus / Xueyi Wang and Jack Snoeyink. Identification of?-Helices from low resolution protein density maps / Alessandro Dal Palu [and others]. Efficient annotation of non-coding RNA structures including pseudoknots via automated filters / Chunmei Liu [and others]. Thermodynamic matchers: strengthening the significance of RNA folding energies / Thomas Hochsmann, Matthias Hochsmann and Robert Giegerich
  • Microarray data analysis and applications. PEM: a general statistical approach for identifying differentially expressed genes in time-course cDNA microarray experiment without replicate / Xu Han, Wing-Kin Sung and Lin Feng. Efficient generalized matrix approximations for biomarker discovery and visualization in gene expression data / Wenyuan Li [and others]
  • Computational genomics and genetics. Efficient computation of minimum recombination with genotypes (not haplotypes) / Yufeng Wu and Dan Gusfield. Sorting genomes by translocations and deletions / Xingqin Qi [and others]. Turning repeats to advantage: scaffolding genomic contigs using LTR retrotransposons / Ananth Kalyanaraman, Srinivas Aluru and Patrick S. Schnable. Whole genome composition distance for HIV-1 genotyping / Xiaomeng Wu [and others]. Efficient recursive linking algorithm for computing the likelihood of an order of a large number of generic markers / S. Tewari, S.M. Bhandarkar and J. Arnold. Optimal Imperfect Phylogeny Reconstruction and Haplotyping (IPPH) / Srinath Sridhar [and others]. Toward an algebraic understanding of haplotype inference by pure parsimony / Daniel G. Brown and Ian M. Harrower. Global correlation analysis between redundant probe sets using a large collection of Arabidopsis ATH1 expression profiling data / Xiangqin Cui and Ann Loraine
  • Motif sequence identification. Distance-based identification of structure motifs in proteins using constrained frequent subgraph mining / Jun Huan [and others]. An improved Gibbs sampling method for motif discovery via sequence weighting / Xin Chen and Tao Jiang. Detection of cleavage sites for HIV-1 protease in native proteins / Liwen You. A methodology for motif discovery employing iterated cluster re-assignment / Osman Abul, Finn Drabls and Geir Kjetil Sandve
  • Biological pathways and systems. Identifying biological pathways via phase decomposition and profile extraction / Yi Zhang and Zhidong Deng. Expectation-maximization algorithms for fuzzy assignment of genes to cellular pathways / Liviu Popescu and Golan Yona. Classification of Drosophila embryonic developmental stage range based on gene expression pattern images / Jieping Ye [and others]. Evolution versus "intelligent design": comparing the topology of protein-protein interaction networks to the internet / Qiaofeng Yang [and others]
  • Protein functions and computational proteomics. Cavity-aware motifs reduce false positives in protein function prediction / Brian Y. Chen [and others]. Protein subcellular localization prediction based on compartment-specific biological features / Chia-Yu Su [and others]. Predicting the binding affinity of MHC class II peptides / Fatih Altiparmak, Altuna Akalin and Hakan Ferhatosmanoglu. Codon-based detection of positive selection can be biased by heterogeneous distribution of polar amino acids along protein sequences / Xuhua Xia and Sudhir Kumar. Bayesian data integration: a functional perspective / Curtis Huttenhower and Olga G. Troyanskaya. An iterative algorithm to quantify the factors influencing peptide fragmentation for MS/MS spectrum / Chungong Yu [and others]. Complexity and scoring function of MS/MS Peptide De Novo sequencing / Changjiang Xu and Bin Ma
  • Biomedical applications. Expectation-maximization method for reconstructing tumor phylogenies from single-cell data / Gregory Pennington [and others]. Simulating in vitro epithelial morphogenesis in multiple environments / Mark R. Grant, Sean H.J. Kim and C. Anthony Hunt. A combined data mining approach for infrequent events: analyzing HIV mutation changes based on treatment history / Ray S. Lin [and others]. A systems biology case study of ovarian cancer drug resistance / Jake Y. Chen [and others].