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Computational biology of cancer : lecture notes and mathematical modeling /

The book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Wodarz, Dominik
Otros Autores: Komarova, Natalia L.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hackensack, NJ : World Scientific, 2005.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface; Contents; Chapter 1 Cancer and somatic evolution; Chapter 2 Mathematical modeling of tumorigenesis; Chapter 3 Cancer initiation: one-hit and two-hit stochastic models; Chapter 4 Microsatellite and chromosomal instability in sporadic and familial cancers; Chapter 5 Cellular origins of cancer; Chapter 6 Costs and benefits of chromosomal instability; Chapter 7 DNA damage and genetic instability; Chapter 8 Tissue aging and the development of cancer; Chapter 9 Basic models of tumor inhibition and promotion; Chapter 10 Mechanisms of tumor neovascularization.