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|a Methods for developing spacecraft water exposure guidelines /
|c Subcommittee on Spacecraft Water Exposure Guidelines, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council.
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|a Developing spacecraft water exposure guidelines
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|a Washington, D.C. :
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|c ©2000.
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|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
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|a Methods for Developing Spacecraft Water Exposure Guidelines -- Copyright -- OTHER REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY -- OTHER REPORTS OF THE COMMITTEE ON TOXICOLOGY -- Preface -- Contents -- Abbreviations -- Executive Summary -- WATER CONTAMINANT SOURCES -- RANKING CONTAMINANTS FOR RISK ASSESSMENT -- DATA FOR ESTABLISHING SWEGS -- RISK ASSESSMENT -- SPECIAL CONSIDERATIONS FOR NASA -- EXPOSURE GUIDELINES SET BY OTHER ORGANIZATIONS -- 1 Introduction -- WATER CONTAMINANTS -- APPROACH TO THE STUDY -- REFERENCES
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|a 2 Sources, Treatment, and Monitoring Of Spacecraft Water ContaminantsOVERVIEW -- DESIGN DRIVERS -- ISS WATER-QUALITY STANDARDS -- SOURCES OF SPACECRAFT WATER CONTAMINATION -- HUMAN URINE -- Untreated Urine -- Chemical Treatment and Distillation By-Products -- HUMIDITY CONDENSATE -- Condensate Sample Results -- Water Recovery Test -- Lunar-Mars Life Support Test Project -- Space Shuttle -- Mir Humidity Condensate -- Environmental Contributors to Spacecraft Humidity Condensate -- Hardware Off-Gassing -- Animal Wastes -- Mechanical Leaks
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|a Microbial MetabolitesPayload Chemicals -- Utility Chemicals -- WASH WATER AND OTHER WASTE STREAMS -- Hygiene Water -- Detergents -- Chemicals from Personal Hygiene Products -- CHeCS Wastes -- CHEMICALS FORMED IN THE WATER TREATMENT SYSTEM -- SYSTEM FAILURES AND INCOMPLETE PROCESSING OF INFLUENT -- CHEMICALS ADDED TO RETARD BACTERIAL GROWTH -- Iodine -- Silver -- REGENERATED WATER -- Inorganic Contaminants -- Shuttle Humidity Condensates -- Mir Humidity Condensates and Mir Reclaimed Water -- LMLSTP 60-d Product Water -- ORGANIC CONTAMINANTS
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|a Humidity Condensate in MirLMLSTP 60-d Product Water -- Stage-10 WRT -- MONITORING WATER CONTAMINANTS -- SOURCE-WATER MONITORING -- In-Line Monitoring and Process Control -- Off-Line Monitoring -- SUMMARY -- REFERENCES -- 3 Sources and Types of Data for Establishing Spacecraft Water Exposure Guidelines -- CHEMICAL AND PHYSICAL CHARACTERISTICS OF A TOXICANT -- HUMAN STUDIES -- ANIMAL STUDIES -- IN VITRO TOXICITY STUDIES -- ADVANCES IN HEALTH EFFECTS ASSESSMENT -- NEUROBEHAVIORAL EFFECTS -- REPRODUCTIVE EFFECTS -- MUTAGENESIS -- MECHANISTIC STUDIES
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|a SUMMARYREFERENCES -- 4 Risk Assessment Methods for Determining Spacecraft Water Exposure Guidelines -- HISTORICAL PERSPECTIVE -- Risk Assessment for Noncarcinogenic Effects -- Risk Assessment for Carcinogenic Effects -- RECOMMENDED APPROACH TO RISK ASSESSMENT -- Exploiting Similarities of Historical Approaches -- Benchmark-Dose Approach to Setting SWEGs -- BMD CALCULATION -- Central Estimate Versus Confidence Limit -- Estimating BMDp for Various Toxic Effects -- EXPOSURE CONVERSION -- Target Tissue Dose -- Differences in Duration -- Species Conversions
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|a National Research Council (U.S.).
|b Subcommittee on Spacecraft Water Exposure Guidelines.
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|t Methods for developing spacecraft water exposure guidelines.
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