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EBSCO_ocn224429381 |
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080416s2008 enka ob 001 0 eng d |
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|a (OCoLC)224429381
|z (OCoLC)249076784
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|a 124337
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|a QP425
|b .N464 2008eb
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|a 612.821
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|a UAMI
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|a Neurochemistry of sleep and wakefulness /
|c edited by Jaime Monti, S.R. Pandi-Perumal, Christopher Michael Sinton.
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260 |
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|a Cambridge ;
|a New York :
|b Cambridge University Press,
|c 2008.
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300 |
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|a 1 online resource (xxiv, 482 pages) :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a Includes bibliographical references and index.
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|a Print version record.
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|a Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.
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|a Cover; Half-title; Title; Copyright; Dedication; Contents; Contributors; Preface; Acknowledgements; Abbreviations; PART I THE NEUROCHEMISTRY OF THE STATES OF SLEEP AND WAKEFULNESS; 1 Neurochemistry of the preoptic hypothalamic hypnogenic mechanism; 2 Neuroanatomical and neurochemical basis of wakefulness and REM sleep systems; 3 Rapid eye movement sleep regulation by modulation of the noradrenergic system; PART II THE INFLUENCE OF NEUROTRANSMITTERS ON SLEEP AND WAKEFULNESS; 4 Gamma-aminobutyric acid and the regulation of paradoxical, or rapid eye movement, sleep
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|a 5 Acetylcholine modulates sleep and wakefulness: a synaptic perspective6 Histamine in the control of sleep-wakefulness; 7 Dopamine in behavioral state control; 8 Glutamate neurotransmission and sleep; 9 Serotonin and sleep-wake regulation; PART III CHANGING PERSPECTIVES; 10 Melatonin and its receptors: biological function in circadian sleep-wake regulation; 11 Sleep regulatory factors; 12 Adenosine and sleep-wake regulation; 13 Prostaglandins and the regulation of sleep and wakefulness; 14 Neuropeptides and sleep-wake regulation
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|a 15 Orexins in sleep and wakefulness: rodent models of narcolepsy-cataplexy16 The relevance of experimental pharmacology to currently available sleep-wake therapeutics; Index
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546 |
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|a English.
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590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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650 |
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|a Sleep
|x Physiological aspects.
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650 |
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|a Neurochemistry.
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650 |
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|a Neuropharmacology.
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650 |
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2 |
|a Neurochemistry
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2 |
|a Neuropharmacology
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|a Sommeil
|x Aspect physiologique.
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650 |
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|a Neurochimie.
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650 |
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|a Neuropharmacologie.
|
650 |
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|a MEDICAL
|x Neuroscience.
|2 bisacsh
|
650 |
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|a PSYCHOLOGY
|x Neuropsychology.
|2 bisacsh
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|a Neurochemistry
|2 fast
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650 |
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|a Neuropharmacology
|2 fast
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|a Sleep
|x Physiological aspects
|2 fast
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700 |
1 |
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|a Monti, Jaime M.
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700 |
1 |
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|a Pandi-Perumal, S. R.
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700 |
1 |
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|a Sinton, Christopher W.
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776 |
0 |
8 |
|i Print version:
|t Neurochemistry of sleep and wakefulness.
|d Cambridge ; New York : Cambridge University Press, 2008
|z 9780521864411
|z 0521864410
|w (OCoLC)171110395
|
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