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Protein condensation : kinetic pathways to crystallization and disease /

The quest to understand the condensation of proteins from solutions is a rapidly evolving field. The purpose of this book is to bring to an interdisciplinary audience the state-of-the-art in current research. The first part of the book deals with issues related to the production of high quality prot...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Gunton, J. D. (James D.), 1937-
Otros Autores: Shiryayev, A. (Andrey), Pagan, D. L. (Daniel L.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, UK ; New York, N.Y. : Cambridge University Press, 2007.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Gunton, J. D.  |q (James D.),  |d 1937- 
245 1 0 |a Protein condensation :  |b kinetic pathways to crystallization and disease /  |c J.D. Gunton, A. Shiryayev, and D.L. Pagan. 
260 |a Cambridge, UK ;  |a New York, N.Y. :  |b Cambridge University Press,  |c 2007. 
300 |a 1 online resource (xii, 364 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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347 |a data file 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
520 |a The quest to understand the condensation of proteins from solutions is a rapidly evolving field. The purpose of this book is to bring to an interdisciplinary audience the state-of-the-art in current research. The first part of the book deals with issues related to the production of high quality protein crystals from solution. Since protein function is determined by structure, high quality protein crystals must be grown in order to determine their structure by X-ray crystallography. The book also discusses diseases that occur due to undesired protein condensation, an increasingly important subject. Examples include sickle cell anemia, cataracts and Alzheimer's disease. Current experimental and theoretical work on these diseases is discussed, which seeks understanding at a fundamental, molecular level, to prevent the undesired condensation from occurring. The book, containing color plate sections, is suitable for graduate students and academic researchers in physics, chemistry, structural biology, protein crystallography and medicine. 
505 0 |a Globular protein structure -- Experimental methods -- Thermodynamics and statistical mechanics -- Protein-protein interactions -- Theoretical studies of equilibrium -- Nucleation theory -- Experimental studies of nucleation -- Lysozyme -- Some other globular proteins -- Membrane proteins -- Crystallins and cataracts -- Sickle hemoglobin and sickle cell anemia -- Alzheimer's disease. 
546 |a English. 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
650 0 |a Proteins. 
650 0 |a Condensation. 
650 0 |a Crystallization. 
650 2 2 |a Crystallization 
650 6 |a Protéines. 
650 6 |a Condensation. 
650 6 |a Cristallisation. 
650 7 |a protein.  |2 aat 
650 7 |a condensation (process)  |2 aat 
650 7 |a crystallization.  |2 aat 
650 7 |a SCIENCE  |x Life Sciences  |x Biochemistry.  |2 bisacsh 
650 7 |a Crystallization  |2 fast 
650 7 |a Condensation  |2 fast 
650 7 |a Proteins  |2 fast 
700 1 |a Shiryayev, A.  |q (Andrey) 
700 1 |a Pagan, D. L.  |q (Daniel L.) 
776 0 8 |i Print version:  |a Gunton, J.D. (James D.), 1937-  |t Protein condensation.  |d Cambridge, UK ; New York, N.Y. : Cambridge University Press, 2007  |z 9780521851213  |z 0521851211  |w (OCoLC)144225234 
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