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Foundations of comparative genomics /

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Mushegian, Arcady R.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press, ©2007.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • The beginning of computational genomics
  • Finding sequence similarities
  • Homology: can we get it right?
  • Getting ready for the era of comparative genomics: the importance of viruses
  • The first fact of comparative genomics: protein sequences are remarkably resilient in evolution
  • The second fact of comparative genomics: functional convergence at the molecular level
  • Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches
  • Prediction of function and reconstruction of metabolism: post-homology approaches
  • Structural genomics: what does it tell us about life?
  • How many protein families are there?
  • Phylogenetic inference and the era of complete genomes
  • Two stories about evolution
  • Minimal and ancestral genomes
  • Comparative genomics and systems biology.