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Target validation in drug discovery /
This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug develo...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Academic Press,
©2007.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Target validation in drug discovery / |c editors, Brian W. Metcalf and Susan Dillon. |
| 260 | |a Amsterdam ; |a Boston : |b Academic Press, |c ©2007. | ||
| 300 | |a 1 online resource (xii, 279 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 520 | |a This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book | ||
| 505 | 0 | |a Section Contents -- I. Pharmaceutical Biotechnology for Target Validation -- II. Target Validation for Biopharmaceutical Drug Discovery -- III. Validating Targets of Small Molecule Approaches. | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Drugs |x Testing. | |
| 650 | 0 | |a High throughput screening (Drug development) | |
| 650 | 0 | |a Drugs |x Design. | |
| 650 | 0 | |a Pharmaceutical technology. | |
| 650 | 1 | 2 | |a Drug Design |
| 650 | 2 | 2 | |a Drug Delivery Systems |
| 650 | 2 | 2 | |a Technology, Pharmaceutical |
| 650 | 6 | |a Médicaments |x Développement. | |
| 650 | 6 | |a Médicaments |x Essais cliniques. | |
| 650 | 6 | |a Criblage à haut débit (Développement des médicaments) | |
| 650 | 6 | |a Médicaments |x Conception. | |
| 650 | 6 | |a Techniques pharmaceutiques. | |
| 650 | 7 | |a MEDICAL |x Drug Guides. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Pharmacy. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Nursing |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Pharmaceutical technology |2 fast | |
| 650 | 7 | |a Drugs |x Design |2 fast | |
| 650 | 7 | |a Drug development |2 fast | |
| 650 | 7 | |a Drugs |x Testing |2 fast | |
| 650 | 7 | |a High throughput screening (Drug development) |2 fast | |
| 650 | 7 | |a Médicaments |x Mise au point. |2 ram | |
| 650 | 7 | |a Médicaments |x Essais cliniques. |2 ram | |
| 650 | 7 | |a Criblage pharmacologique. |2 ram | |
| 700 | 1 | |a Metcalf, Brian W. | |
| 700 | 1 | |a Dillon, Susan, |d 1952- | |
| 776 | 0 | 8 | |i Print version: |t Target validation in drug discovery. |d Amsterdam ; Boston : Academic Press, ©2007 |z 0123693934 |z 9780123693938 |w (DLC) 2006049868 |w (OCoLC)70823305 |
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