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Practical process research & development /
This book will provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R & D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
©2000.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Foreword by K. Barry Sharpless. Foreword by Jerome L. Moniot. Preface. About the Author. Approaches to Process Development. Route Selection. Reagent Selection. Solvent Selection. Running the Reaction. Effects of Water. In-Process Controls. Optimizing the Reaction by Minimizing Impurities. Optimizing Catalytic Reactions. Work-Up. Tools for Purifying the Product: Column Chromatography, Crystallization, and Reslurrying. Final Product Form and Impurity Considerations. Vessels and Mixing. Preparing for and Implementing the Scale-up Run. Troubleshooting. Chiral Syntheses. General Index. Reaction Type Index. Reagent Index.