Aging of the genome : the dual role of DNA in life and death /

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Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible unive...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Vijg, Jan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford ; New York : Oxford University Press, 2007.
Temas:
Aging > Genetic aspects.
Apoptosis.
Genomes.
Developmental genetics.
DNA damage.
Aging > genetics
Apoptosis
DNA Damage
DNA > genetics
Genome
Vieillissement > Aspect génétique.
Apoptose.
Génomes.
Génétique du développement.
ADN > Lésions.
MEDICAL > Neuroscience.
PSYCHOLOGY > Neuropsychology.
Acceso en línea:Texto completo
Descripción
Sumario:Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol.
Descripción Física:1 online resource (x, 372 pages) : illustrations
Bibliografía:Includes bibliographical references (pages 309-351) and index.
ISBN:9780191524585
0191524581
9781429469937
1429469935
0198569238
9780198569237

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