Application of toxicogenomics to cross-species extrapolation : report of a workshop /

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Considers strategies for communicating toxicogenomic information to the public and other non-expert audiences, specifically addressing the communication of some key social, ethical, and legal issues related to toxicogenomics and addressing how information related to the social implications of toxico...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: National Research Council (U.S.). Committee on Applications of Toxicogenomics to Cross-Species Extrapolation
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, ©2006.
Colección:Online access: NCBI NCBI Bookshelf.
Temas:
Toxicology.
Environmental sciences.
Toxicogenetics
Toxicology
Toxicologie.
Sciences de l'environnement.
toxicology.
environmental sciences.
HEALTH & FITNESS > Diseases > Genetic.
MEDICAL > Genetics.
Environmental sciences
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Emerging molecular and computational approaches for cross-species extrapolation
  • Potential implications of genomics for risk assessment
  • Technological challenges of cross-species extrapolation using proteomics
  • Modeling gene-expression data to predict human hepatotoxicity after inconsistent animal responses
  • Using metabolomics to explore species differences in metabolism and distribution
  • A systems-biology approach to cross-species extrapolation
  • Combining transcriptional and toxicologic approaches to understanding the basis of species differences in conazole carcinogenesis
  • Species differences in response to perfluorooctanoic acid.

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