Gene genealogies, variation and evolution : a primer in coalescent theory /

"This text presents a straightforward and elementary account of coalescent theory, which is a central concept in the study of genetic sequence variation observed in a population. Authored by leading experts, and rich in examples and illustrations, Gene Genealogies, Variation and Evolution is hi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Hein, Jotun
Otros Autores: Schierup, Mikkel H., Wiuf, Carsten
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford ; New York : Oxford University Press, 2005.
Temas:
Population genetics > Mathematical models.
Population genetics.
Gene mapping.
Genetics > Mathematical models.
Genetics, Population
Chromosome Mapping
Models, Genetic
Génétique > Modèles mathématiques.
Génétique des populations.
Cartes chromosomiques.
SCIENCE > Life Sciences > Genetics & Genomics.
Population genetics
Genetics > Mathematical models
Gene mapping
Population genetics > Mathematical models
Evolution
Genanalyse
Mathematisches Modell
Populationsgenetik
Rekombination
Genetik
Koaleszenz
Populatiegenetica.
Coalescentie.
Variaties.
Biometrie.
Genetica de populacʹoes (modelos matematicos)
Genetica (evolucʹao)
nucleotidenvolgordes
nucleotide sequences
dna sequencing
genetische variatie
genetic variation
genetische diversiteit
genetic diversity
populatiegenetica
population genetics
gegevensanalyse
data analysis
waarschijnlijkheidstheorie
probability theory
Population and Quantitative Genetics
Kwantitatieve- en populatiegenetica
Acceso en línea:Texto completo
Tabla de Contenidos:
  • The basic coalescent
  • A Y-chromosome data set
  • Data and theory
  • The Wright-Fisher model
  • Assumptions of the Wright-Fisher model
  • The number of descendants of a gene in one generation
  • The geometric distribution
  • The exponential distribution
  • The discrete-time coalescent
  • Coalescence of a sample of two genes
  • Coalescence of a sample of n genes
  • Example: Effect of approximations
  • The continuous time coalescent
  • Calculating simple quantities on a coalescent tree
  • The height of a tree
  • The total branch length of a tree
  • The effect of sampling more sequences
  • The effective population size
  • The Moran model
  • Robustness of the coalescent
  • From genealogies to sequences
  • Mathematical models of alleles
  • The infinite alleles model
  • The infinite sites model
  • Finite sites model
  • The Wright-Fisher model with mutation
  • Algorithms for simulating sequence evolution
  • The probability of a sample configuration
  • Infinite alleles model
  • Infinite sites model
  • Impossible ancestral states
  • Quantities related to the infinite sites model
  • The number of segregating sites
  • Haplotypes
  • Pairwise mismatch distribution
  • Estimators of [theta] and Tajima's D
  • Evolutionary versus sampling variance
  • Example 1: The variable S[subscript n]
  • Example 2: Tajima's estimator [pi]
  • Trees and topologies
  • Some terminology
  • The jump process and the waiting time process
  • The coalescent and phylogenetic trees
  • Counting trees and topologies
  • Gene trees
  • How to build a gene tree.

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