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Conformational proteomics of macromolecular architecture : approaching the structure of large molecular assemblies and their mechanisms of action /

Biological processes involving large macromolecular assemblies arethought to be a dynamic consequence of cooperativity andmetastability. The folding of a peptide chain creates localenvironments from which "activity" can emerge. In the same way, theassembly of large molecular complexes crea...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Cheng, R. Holland, Hammar, Lena
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Singapore ; River Edge, NJ : World Scientific Pub., ©2004.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:Biological processes involving large macromolecular assemblies arethought to be a dynamic consequence of cooperativity andmetastability. The folding of a peptide chain creates localenvironments from which "activity" can emerge. In the same way, theassembly of large molecular complexes creates dynamic features thatwould only be feasible in a large construct. The biologicalimplications of such adaptation will be explored as it applies to thestatic quasisymmetry situations, as well as to the dynamics ofstructural transitions. The current wealth of solved high-resolutioncomplex structures makes th
Descripción Física:1 online resource (xi, 420 pages) : illustrations (some color)
Bibliografía:Includes bibliographical references and index.
ISBN:9812562648
9789812562647
1281347698
9781281347695