Health implications of perchlorate ingestion /

Perchlorate a powerful oxidant used in solid rocket fuels by the military and aerospace industry has been detected in public drinking water supplies of over 11 million people at concentrations of at least 4 parts per billion (ppb). High doses of perchlorate can decrease thyroid hormone production by...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: National Research Council (U.S.). Division of Earth Sciences
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, ©2005.
Temas:
Perchlorates > Physiological effect.
Drinking water > Contamination.
Rats.
Risk assessment.
Water-supply.
Human beings.
Animals
Humans
Rats
Perchloric Acid > adverse effects
Thyroid Gland > physiology
Environmental Exposure
Risk Assessment
Water Supply
Perchlorates > Effets physiologiques.
Eau potable > Contamination.
Exposition (Toxicologie)
Évaluation du risque.
Eau > Approvisionnement.
Êtres humains.
risk assessment.
Homo sapiens (species)
POLITICAL SCIENCE > Political Freedom & Security > Law Enforcement.
Water-supply
Risk assessment
Drinking water > Contamination
United States
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Summary
  • 1. Introduction
  • 2. The thyroid and disruption of thyroid function in humans
  • 3. Epidemiologic studies of occupational and environmental exposures to perchlorate
  • 4. Animal studies
  • 5. Risk characterization of perchlorate
  • 6. Research recommendations
  • Appendix A. Biographic information on the Committee to Assess the Health Implications of Perchlorate Ingestion
  • Appendix B. Glossary
  • Appendix C. Participants at public sessions
  • Appendix D. Sensitivity of perchlorate-induced iodide uptake inhibition to serum iodide concentrations
  • Appendix E. Physiologically based pharmacokinetic modeling.

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