RNA interference technology : from basic science to drug development /

RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. In this cutting-edge overview, the basic concepts of RNAi biology are discussed, as well as the current and potential applications, providing an invaluable reference for all those who need to un...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Appasani, Krishnarao
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, UK ; New York : Cambridge University Press, 2005.
Temas:
Small interfering RNA.
Gene silencing.
RNA, Small Interfering
Gene Silencing
Petits ARN interférents.
Inactivation génique.
SCIENCE > Life Sciences > Molecular Biology.
RNA, Small Interfering.
Gene silencing
Small interfering RNA
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Half-title; Title; Copyright; Dedication; Contents; Foreword; Foreword; Contributors; Introduction; SECTION ONE Basic RNAi, siRNA, microRNAs and gene-silencing mechanisms; SECTION TWO Design, synthesis of siRNAs; SECTION THREE Vector development and in vivo, in vitro and in ovo delivery methods; SECTION FOUR Gene silencing in model organisms; SECTION FIVE Drug target validation; SECTION SIX Therapeutic and drug development; SECTION SEVEN High-throughput genome-wide RNAi analysis; Index.

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