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|a Cells, aging, and human disease /
|c Michael B. Fossel.
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|a Includes bibliographical references (pages 291-468) and index.
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|a 1. The context -- 2. Cell senescence -- 3. Cell senescence in aging -- 4. The aging cascade -- 5. Cancer -- 6. Parasitic disease -- 7. The progerias -- 8. The skin -- 9. Cardiovascular system -- 10. Orthopedic systems -- 11. Hematopoetic and immune systems -- 12. Endocrine system -- 13. Nervous system -- 14. Kidneys -- 15. Muscle -- 16. Gastrointestinal system -- 17. The eye -- 18. Towards therapy.
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|a "Cells, Aging, and Human Disease examines aging from genes to clinical application, analyzing the cellular changes that underlie human age-related disease. The text explores both the fundamental processes of human aging and tissue-by-tissue pathology, as it details current research and state-of-the-art clinical interventions in aging and age-related disease." "Emphasizing human cell mechanisms, the first section of the book presents and analyzes our current knowledge of telomere biology and cell senescence. The text brings the reader up-to-date on telomere maintenance and dynamics. It explains both the limited and general model of cell senescence as the central component in human clinical aging."--Jacket.
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|a Electronic reproduction.
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|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
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|a Aging.
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|a Fossel, Michael.
|t Cells, aging, and human disease.
|d Oxford ; New York : Oxford University Press, 2004
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