Tabla de Contenidos:
  • PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
  • Contents
  • Genetic engineering of viruses and of virus vectors: A preface
  • Site-specific integration by adeno-associated virus
  • Oncogenic potential of the adenovirus E4orf6 protein
  • MATERIALS AND METHODS
  • RESULTS
  • DISCUSSION
  • Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
  • MATERIALS AND METHODS
  • RESULTS
  • DISCUSSION
  • The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors
  • Genome Structure and Gene ContentThe Role of Selected Viral Genes in Viral Replication
  • The Function of Viral Genes in Latency
  • Genetic Engineering of Novel Viral Genomes
  • Requirements and Design of Viral Vectors
  • Conclusions
  • The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors
  • Direct Virus Therapy
  • Conclusion
  • Replication-defective herpes simplex virus vectors for gene transfer in vivo
  • A deletion mutant in the human cytomegalovirus gene encoding IE1491aa is replication defective due to a failure inâ€? MATERIALS AND METHODS
  • RESULTS
  • DISCUSSION
  • Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains
  • MATERIALS AND METHODS
  • RESULTS
  • DISCUSSION
  • Epstein-Barr virus vectors for gene delivery to B lymphocytes
  • MATERIALS AND METHODS
  • RESULTS AND DISCUSSION
  • Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety
  • Applications of pox virus vectors to vaccination: An updateVaccinia-Rabies Glycoprotein G Recombinant
  • Fowlpox Virus-Based Recombinants
  • Avipox Virus Vectors in Nonavian Species
  • Attenuated Vaccinia-Based Vector: NYVAC
  • Other Applications of Pox Virus-Based Vectors
  • Discussion
  • Negative-strand RNA viruses: Genetic engineering and applications
  • DNA-Containing Viruses
  • Positive-Strand RNA Viruses
  • Introduction of cDNA-Derived RNA into a Negative-Strand RNA Virus (Influenza Virus)
  • Plasmid-Based Reverse Genetics System for Influenza Virus
  • Chimeric Influenza Viruses Expressing Foreign Epitopes or PolypeptidesRescue of Infectious Rabies Virus from cDNA
  • Rescue of Other Nonsegmented Negative-Strand RNA Viruses
  • Perspective
  • Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virusâ€?
  • MATERIALS AND METHODS
  • RESULTS
  • DISCUSSION
  • Specific infection of CD4+ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein
  • MATERIALS AND METHODS
  • RESULTS
  • DISCUSSION