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Computer-assisted modeling : contributions of computational approaches to elucidating macromolecular structure and function /

In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule--polymers formed from families of simpler subunits. Because of their size and complexity, the p...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: National Research Council (U.S.). Committee on Computer-Assisted Modeling
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press, 1987.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Computer-assisted modeling :  |b contributions of computational approaches to elucidating macromolecular structure and function /  |c Committee on Computer-Assisted Modeling, Board on Basic Biology, Commission on Life Sciences, National Research Council. 
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520 3 |a In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule--polymers formed from families of simpler subunits. Because of their size and complexity, the polymers are capable of both inter- and intramolecular interactions. These interactions confer upon the polymers distinctive three-dimensional shapes. These tertiary configurations, in turn, determine the function of the macromolecule. Computers have become so inextricably involved in empirical studies of three-dimensional macromolecular structure that mathematical modeling, or theory, and experimental approaches are interrelated aspects of a single enterprise. 
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