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DNA microarrays and gene expression : from experiments to data analysis and modeling /

DNA microarrays are revolutionizing biology and medicine. They can provide a snapshot of the level of gene expression in a cell and are therefore a powerful tool with which to study biological phenomena at the molecular level. This inter-disciplinary introduction will be essential reading for resear...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Baldi, Pierre
Otros Autores: Hatfield, G. Wesley, 1940-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, U.K. ; New York : Cambridge University Press, 2002.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Half-title; Title; Copyright; Contents; Preface; 1 A brief history of genomics; 2 DNA array formats; 3 DNA array readout methods; 4 Gene expression profiling experiments: Problems, pitfalls, and solutions; 5 Statistical analysis of array data: Inferring changes; 6 Statistical analysis of array data: Dimensionality reduction, clustering, and regulatory regions; 7 The design, analysis, and interpretation of gene expression profiling experiments; 8 Systems biology; Appendix A; Appendix B; Appendix C; Appendix D; Index.