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Growth factors and receptors : a practical approach /
Growth factors are extra-cellular molecules that interact with receptors on the cell surface to initiate a sequence of events culminating in transcription of DNA prior to cell division. Disturbances in the production of growth factors or the sensitivity of their receptors are important in tumour gro...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford [England] ; New York :
Oxford University Press,
1998.
|
| Colección: | Practical approach series ;
194. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Growth factors and receptors : |b a practical approach / |c edited by Ian A. McKay and Kenneth D. Brown. |
| 260 | |a Oxford [England] ; |a New York : |b Oxford University Press, |c 1998. | ||
| 300 | |a 1 online resource (xxii, 266 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Practical approach series ; |v 194 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |6 880-01 |a Intro; Contents; List of contributors; Abbreviations; 1. Engineered growth factors and receptors, and their applications; 1. Introduction; Known growth factors and receptors; Modes of factor-receptor interaction; 2. Applications of engineered growth factors and receptors; 3. Principal methods for engineering growth factors and their receptors; Mutagenesis; Formation of chimeric proteins; Manufacture of alternative ligands and receptors; 4. Design of engineered growth factors and receptors; DNA sequence of factor or receptor to be engineered. | |
| 505 | 8 | |a Analysis of existing DNA sequence for useful restriction sitesDesign of wholly synthetic growth factors and receptors; 5. Expression of DNAs encoding growth factors or receptors; Deciding on an expression system; Microbial expression; In vitro expression; Eukaryotic gene expression; Acknowledgements; References; 2. Engineering of novel neurotrophins; 1. Introduction; 2. Structure-function analyses of neurotrophins; 3. Site-directed mutagenesis; Kunkel method; PCR-based mutagenesis; 4. Expression of recombinant protein; COS cell expression; Baculovirus expression. | |
| 520 | |a Growth factors are extra-cellular molecules that interact with receptors on the cell surface to initiate a sequence of events culminating in transcription of DNA prior to cell division. Disturbances in the production of growth factors or the sensitivity of their receptors are important in tumour growth. Therefore, there is much interest in engineering both growth factors and their receptors to intervene in cancer. This book describes a variety of techniques for theengineering, analysis, definition of function and detection of gene expression of growth factors and their receptors. A number of p. | ||
| 590 | |a eBooks on EBSCOhost |b EBSCO eBook Subscription Academic Collection - Worldwide | ||
| 650 | 0 | |a Growth factors |v Laboratory manuals. | |
| 650 | 0 | |a Growth factors |x Receptors |v Laboratory manuals. | |
| 650 | 0 | |a Genetic engineering |v Laboratory manuals. | |
| 650 | 0 | |a Gene therapy |x Research |v Laboratory manuals. | |
| 650 | 0 | |a Growth factors. | |
| 650 | 0 | |a Gene therapy. | |
| 650 | 1 | 2 | |a Growth Substances |
| 650 | 2 | 2 | |a Genetic Therapy |
| 650 | 2 | 2 | |a Receptors, Growth Factor |
| 650 | 6 | |a Facteurs de croissance |v Manuels de laboratoire. | |
| 650 | 6 | |a Facteurs de croissance |x Récepteurs |v Manuels de laboratoire. | |
| 650 | 6 | |a Thérapie génique |x Recherche |v Manuels de laboratoire. | |
| 650 | 6 | |a Facteurs de croissance. | |
| 650 | 6 | |a Thérapie génique. | |
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| 650 | 7 | |a Gene therapy |x Research |2 fast | |
| 650 | 7 | |a Genetic engineering |2 fast | |
| 650 | 7 | |a Growth factors |2 fast | |
| 650 | 7 | |a Growth factors |x Receptors |2 fast | |
| 655 | 2 | |a Laboratory Manual | |
| 655 | 7 | |a Laboratory manuals |2 fast | |
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| 700 | 1 | |a McKay, Ian |q (Ian A.) | |
| 700 | 1 | |a Brown, Kenneth D. | |
| 776 | 0 | 8 | |i Print version: |t Growth factors and receptors. |d Oxford [England] ; New York : Oxford University Press, 1998 |z 0199636478 |z 019963646X |w (DLC) 98009879 |w (OCoLC)38249246 |
| 830 | 0 | |a Practical approach series ; |v 194. | |
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