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|b N2767c 2000
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|a UAMI
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|a Copper in drinking water /
|c Committee on Copper in Drinking Water, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council.
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|a Washington, D.C. :
|b National Academy Press,
|c ©2000.
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|a 1 online resource (147 pages) :
|b illustrations
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
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|a data file
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|a "This project was supported by Cooperative Agreement No. CR827277-01 between the National Academy of Sciences and the U.S. Environmental Protection Agency"--Title page verso
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|a Includes bibliographical references.
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|a Print version record.
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|a Copper in Drinking Water -- Copyright -- Preface -- Contents -- Executive Summary -- THE CHARGE TO THE COMMITTEE -- THE COMMITTEE'S APPROACH TO ITS CHARGE -- THE COMMITTEE'S EVALUATION -- Health Effects of Excess Copper -- Recommendations -- Physiological Role of Copper -- Recommendations -- Sensitive Populations -- Recommendations -- Risk Characterization -- Recommendations -- 1 Introduction -- CHEMICAL AND PHYSICAL PROPERTIES -- SOURCES OF COPPER IN DRINKING WATER -- COMMITTEE'S APPROACH TO ITS CHARGE -- STRUCTURE OF THE REPORT -- REFERENCES
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|a 2 Physiological Role of CopperESSENTIALITY -- BIOCHEMISTRY AND PHYSIOLOGY -- FACTORS AFFECTING BIOAVAILABILITY -- Effect of Age -- Dietary and Other Interactions -- CONCLUSIONS -- RECOMMENDATIONS -- REFERENCES -- 3 Health Effects of Copper Deficiencies -- TERATOGENESIS OF COPPER DEFICIENCY -- Causes of Copper Deficiency -- Copper in Prenatal Development -- Drug-Induced Copper Deficiency -- Disease-Induced Copper Deficiency -- Copper-Diet Interactions -- Gene-Induced Copper Deficiency -- Human Copper Deficiency and Teratogenesis
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|a Primary Dietary Copper DeficiencyHEALTH EFFECTS OF COPPER DEFICIENCIES IN ADULTS -- CONCLUSIONS -- REFERENCES -- 4 Disorders of Copper Homeostasis -- MENKES DISEASE -- OCCIPITAL HORN SYNDROME -- WILSON DISEASE -- GENETIC CHARACTERISTICS OF WILSON AND MENKES DISEASES -- HETEROZYGOTES FOR WILSON DISEASE -- ACERULOPLASMINEMIA -- TYROLEAN INFANTILE CIRRHOSIS -- INDIAN CHILDHOOD CIRRHOSIS -- IDIOPATHIC COPPER TOXICOSIS -- OTHER GENETIC DISORDERS -- DISEASE-INDUCED CHANGES IN COPPER HOMEOSTASIS -- CONCLUSIONS -- RECOMMENDATIONS -- REFERENCES
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|a 5 Health Effects of Excess CopperACUTE TOXICITY -- Case Reports and Population-Based Studies -- CHRONIC TOXICITY -- Reproductive and Developmental Toxicity -- Genotoxicity, Mutagenicity, and Carcinogenicity of Copper -- Sensitive Populations -- Carriers of Genetic Defects in Copper Homeostasis -- Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) -- ANIMAL STUDIES -- Toxicity in Animals -- Reproductive and Developmental Toxicity -- Neurotoxicity -- Carcinogenicity -- Mechanisms and Animal Models for Copper Toxicity -- Mechanism of Acute Copper Toxicity
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|a Mechanism of Chronic Copper ToxicityCONCLUSIONS -- RECOMMENDATIONS -- REFERENCES -- 6 Risk Characterization -- COPPER DEFICIENCY -- COPPER TOXICITY FROM SINGLE OR SHORT-TERM EXPOSURE -- COPPER TOXICITY FROM CHRONIC EXPOSURE -- Sensitive Populations -- Carriers of the Wilson-Disease Gene and Other Genetically Sensitive Groups -- Infants -- Chronic Liver Disease -- Glucose-6-Phosphate Dehydrogenase Deficiency -- Implications for the MCLG -- CHRONIC COPPER EXPOSURE THROUGH TAP WATER -- DIETARY CONTRIBUTION AND TOTAL COPPER INTAKE -- Formula-Fed Infants
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546 |
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|a English.
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590 |
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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650 |
|
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|a Copper
|x Toxicology.
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650 |
|
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|a Drinking water
|x Copper content.
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|a Copper
|x Metabolism
|x Disorders.
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1 |
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|a Copper
|x adverse effects
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2 |
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|a Copper
|x physiology
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2 |
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|a Environmental Exposure
|x standards
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|a Water Supply
|x standards
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|a Cuivre
|x Toxicologie.
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|a Eau potable
|x Teneur en cuivre.
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|a Cuivre
|x Troubles du métabolisme.
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|a TECHNOLOGY & ENGINEERING
|x Environmental
|x Water Supply.
|2 bisacsh
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|a Copper
|x Metabolism
|x Disorders
|2 fast
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7 |
|a Copper
|x Toxicology
|2 fast
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|a Drinking water
|x Copper content
|2 fast
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|a Drinkwater.
|2 gtt
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|a Koper.
|2 gtt
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1 |
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|a Toxicologie.
|2 gtt
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710 |
2 |
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|a National Research Council (U.S.)
|
776 |
0 |
8 |
|i Print version:
|t Copper in drinking water.
|d Washington, D.C. : National Academy Press, ©2000
|z 0309069394
|w (DLC) 00102668
|
856 |
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