Biologic markers in reproductive toxicology /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: National Research Council (U.S.). Subcommittee on Reproductive and Neurodevelopmental Toxicology
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press, 1989.
Temas:
Reproductive toxicology.
Biochemical markers.
Biomarkers
Environmental Pollutants > adverse effects
Reproduction
Toxicologie de la reproduction.
Marqueurs biologiques.
MEDICAL > Reproductive Medicine & Technology.
Biochemical markers
Reproductive toxicology
Fortpflanzung
Toxikologie
Biomarker
Aufsatzsammlung
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Executive summary
  • Report of the Oversight Committee. I. Biologic markers in male reproductive and gametic genetic toxicology. Introduction
  • Clinical evaluation of male infertility
  • Biologic markers of testicular function
  • Biologic markers of epididymal structure and function
  • Biologic markers of accessory sex organ structure and function
  • Biologic markers of human male reproductive health and physiologic damage
  • Assessing transmitted mutations in mice
  • Markers for measuring germinal genetic toxicity and heritable mutations in people
  • Conclusions and recommendations. II. Biologic markers in female reproductive toxicology. Introduction
  • Biologic markers of genetic damage in females
  • Biologic markers of reproductive development and aging
  • Biologic markers of nonconceptive menstrual cycles
  • Developing assays of biologic markers for epidemiologic studies: experience with a marker of pregnancy and early loss
  • Conclusions and recommendations. III. Biologic markers of toxicity during pregnancy. Introduction
  • Molecular biology: developing DNA markers of genotoxic effects
  • Reproductive immunology: biologic markers of compromised pregnancies
  • Cell biology: identifying biologic markers expressed during early pregnancy
  • Physiologic assessment of fetal compromise
  • Conclusions and Recommendations. IV. Biologic Markers in Neurodevelopmental Toxicology. Introduction
  • Developmental neurobiology of the central nervous system
  • Morphologic, neurochemical, and behavioral responses to toxic agents
  • Methodologic issues of extrapolation from animal studies to human toxicant exposure
  • Lead as a paradigm for the study of neurodevelopmental toxicology
  • Conclusions and recommendations
  • Appendix: Assessing the validity of biologic markers: alpha-fetoprotein
  • References
  • Biographies
  • Index.

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