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|a Biologic markers in reproductive toxicology /
|c Subcommittee on Reproductive and Neurodevelopmental Toxicology, Committee on Biologic Markers, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council.
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|a Washington, D.C. :
|b National Academy Press,
|c 1989.
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|a 1 online resource (xxi, 395 pages) :
|b illustrations
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|a text
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|a Includes bibliographical references (pages 319-372) and index.
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|a Executive summary -- Report of the Oversight Committee. I. Biologic markers in male reproductive and gametic genetic toxicology. Introduction -- Clinical evaluation of male infertility -- Biologic markers of testicular function -- Biologic markers of epididymal structure and function -- Biologic markers of accessory sex organ structure and function -- Biologic markers of human male reproductive health and physiologic damage -- Assessing transmitted mutations in mice -- Markers for measuring germinal genetic toxicity and heritable mutations in people -- Conclusions and recommendations. II. Biologic markers in female reproductive toxicology. Introduction -- Biologic markers of genetic damage in females -- Biologic markers of reproductive development and aging -- Biologic markers of nonconceptive menstrual cycles -- Developing assays of biologic markers for epidemiologic studies: experience with a marker of pregnancy and early loss -- Conclusions and recommendations. III. Biologic markers of toxicity during pregnancy. Introduction -- Molecular biology: developing DNA markers of genotoxic effects -- Reproductive immunology: biologic markers of compromised pregnancies -- Cell biology: identifying biologic markers expressed during early pregnancy -- Physiologic assessment of fetal compromise -- Conclusions and Recommendations. IV. Biologic Markers in Neurodevelopmental Toxicology. Introduction -- Developmental neurobiology of the central nervous system -- Morphologic, neurochemical, and behavioral responses to toxic agents -- Methodologic issues of extrapolation from animal studies to human toxicant exposure -- Lead as a paradigm for the study of neurodevelopmental toxicology -- Conclusions and recommendations -- Appendix: Assessing the validity of biologic markers: alpha-fetoprotein -- References -- Biographies -- Index.
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|f Restrictions unspecified
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|a Electronic reproduction.
|b [Place of publication not identified] :
|c HathiTrust Digital Library,
|d 2010.
|5 MiAaHDL
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|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
|u http://purl.oclc.org/DLF/benchrepro0212
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|a Print version record.
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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|a Reproductive toxicology.
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|a Biochemical markers.
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|a Environmental Pollutants
|x adverse effects
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|a Reproduction
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|a Toxicologie de la reproduction.
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|a Marqueurs biologiques.
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|a MEDICAL
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|a Biochemical markers
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|a Reproductive toxicology
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|a Toxikologie
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|a National Research Council (U.S.).
|b Subcommittee on Reproductive and Neurodevelopmental Toxicology.
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776 |
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|i Print version:
|t Biologic markers in reproductive toxicology.
|d Washington, D.C. : National Academy Press, 1989
|z 0309039797
|w (DLC) 89003071
|w (OCoLC)19268308
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