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Evidence-Based Evolutionary Medicine

Conclusions -- References -- Chapter 5 The Cell as the Smallest Functional Unit of Biology/Physiology -- Summary -- In the Beginning -- The Advent of Multicellularity -- Evolution: Cellular Style -- The Water-Land Transition and Vertebrate Evolution -- The Cellular Approach to Evolution Is Predictiv...

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Detalles Bibliográficos
Autor principal: Torday, John S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Newark : John Wiley & Sons, Incorporated, 2018.
Colección:New York Academy of Sciences Ser.
Acceso en línea:Texto completo

MARC

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245 1 0 |a Evidence-Based Evolutionary Medicine  |h [electronic resource]. 
260 |a Newark :  |b John Wiley & Sons, Incorporated,  |c 2018. 
300 |a 1 online resource (259 p.). 
490 1 |a New York Academy of Sciences Ser. 
500 |a Description based upon print version of record. 
505 0 |a Intro -- Title Page -- Copyright Page -- Contents -- Preface -- Chapter 1 A Brief History of Evolutionary Thinking -- Summary -- Introduction -- Darwin -- Darwin's Theory -- The Modern Synthesis -- The Darkest Chapter -- Conclusions -- References -- Chapter 2 Outlining the Major Transitions in the History of Life -- Summary -- Introduction -- The Major Transitions -- Conclusions -- References -- Chapter 3 One Central Mystery: Why Did Eukaryotes Only Evolve Once? -- Summary -- Introduction -- Conclusions -- References -- Chapter 4 A Levels-of-Selection View of Evolutionary Physiology 
520 |a Conclusions -- References -- Chapter 5 The Cell as the Smallest Functional Unit of Biology/Physiology -- Summary -- In the Beginning -- The Advent of Multicellularity -- Evolution: Cellular Style -- The Water-Land Transition and Vertebrate Evolution -- The Cellular Approach to Evolution Is Predictive -- We Are Not Just in This Environment, We Are of It -- Bioethics Based on Evolutionary Ontology and Epistemology, Not Descriptive Phenotypes, and Genes -- The Theory of Everything (TOE) -- Coda -- References -- Chapter 6 Development of Tissues and Organs -- Summary -- Introduction 
505 8 |a The Lung as an Interactive Barrier: Homolog of the Plasma Membrane, Skin, and Brain -- NKX2.1, Thyroid, Pituitary, and Lung Pleiotropy -- The Phylogeny of the Thyroid -- An Evolutionary Vertical Integration of the Phylogeny and Ontogeny of the Thyroid -- A Retrospective Understanding of Evolution -- Denouement -- Conclusions -- References -- Chapter 8 Wnt Signaling During Development -- Summary -- Introduction -- Role of Growth Factors in Alveolar Homeostasis -- The Kidney Glomerulus as a Homolog of the Lung Alveolus -- Pathologic Consequences of Failed Paracrine Signaling -- Reference 
500 |a Evolution of Endothermy/Homeothermy as Evidence for the Effect of Stress on Vertebrate Physiologic Evolution 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
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830 0 |a New York Academy of Sciences Ser. 
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880 8 |6 505-00/(S  |a Lung Alveolar Morphogenesis -- Parathyroid Hormone-Related Protein -- Stretch-Induced Cell-Cell Interactions -- References -- Chapter 7 When Homeostasis Fails -- Summary -- Introduction -- Peroxisome Proliferator Activated Receptor Gamma as a Connection to the Evolution of the LIF -- PPARγ, Statins, and TOR as Mechanisms for Homeostasis -- Homeostatic Control of What-- Pleiotropy: The Deus ex Machina (Ghost in the Machine) -- Rubik's Cube as a Metaphor for Pleiotropic Evolution -- The Lung as the Prototypical Pleiotropic Mechanism 
880 8 |6 505-00/(S  |a Chapter 9 Integrated Regulation of Homeostasis - Vascular, Nervous, Endocrine, Neuroendocrine, Autonomic -- Summary -- Introduction -- Water-Land Transition as the Catalyst for Vertebrate Evolution -- Parathyroid Hormone-Related Protein Signaling Is Key to Understanding the Evolution of the Lung -- The Physics of Lung Evolution -- Functional Homology between Membrane Lipids and Oxygenation -- Atmospheric Oxygen, Physiologic Stress, Gene Duplication, and Lung Evolution -- Duplication of the β Adrenergic Receptor and the Glucocorticoid Receptor Genes 
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